Unique Drug ADRs Flashcards

1
Q

Methyldopa

A

Positive ANA

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2
Q

Sensipar

A

Hypocalcemia

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3
Q

Flomax

A

Intraoperative floppy iris syndrome in cataract surgery patients

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4
Q

Viberzi

A

Sphincter of Oddi

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5
Q

Tysabri

A

PML

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6
Q

Entyvio

A

PML

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7
Q

PTU and methimazole

A

Hepatitis, agranuloytosis

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8
Q

Carbonic anhydrase inhibitors

A

blepharitis

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9
Q

Isotretinoin

A

Night-time vision problems

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10
Q

Alpha-blockers

A

Floppy iris syndrome

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11
Q

Amiodarone

A

corneal deposits

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12
Q

Digoxin

A

yellow-green vision toxicity

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13
Q

Ethambutol

A

optic neuropathy

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14
Q

Voriconazole

A

color vision change

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15
Q

Linezolid

A

vision changes

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16
Q

Tamoxifen

A

vision changes

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17
Q

Lithium

A

osteoporosis

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18
Q

Anticonvulsants (CBZ, phenytoin, phenobarbital)

A

osteoporosis

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19
Q

Bisphosphonates

A

osteonecrosis of the jaw

20
Q

Teriparitide and Abaloparatide

A

osteosarcoma

21
Q

Prolia

A

osteonecrosis of the jaw

22
Q

Propofol

A

increase in TG

23
Q

Bile acid sequestrants

A

Bleeding risk (vit k deficiency)

24
Q

Calcium channel blockers

A

gingival hyperplasia

25
Hydralazine
butterfly rash
26
Benicar
Sprue like enteropathy
27
Minocycline
DILE
28
Linezolid
Myelosuppression, peripheral and optic neuropathy
29
Isoniazid
DILE
30
Pyrazinamide
Hyperuricemia
31
Ethambutol
Optic neuritis
32
Voriconazole
Optic neuritis
33
Televancin, Daptomycin, Ortiavancin and Dalbavancin
False INR/PT increase
34
Televancin
Metallic taste
35
Metronidazole
Metallic taste, peripheral neuropathies
36
Daptomycin
myopathy and rhabdo
37
Tigecycline
Increased risk of death
38
Synercid
Arthalgias, myalgias, infusion rxns, phlebitis, hyperbilirubinemia
39
Chloramphenicol
Gray man syndrome, myelosuppression
40
Clarithromycin
metallic taste
41
Echinocandins
Histamine-related reactions
42
Ribavirin
Hemolytic Anemia
43
Viread and Vemlidy (tenofovir)
Fanconi syndrome, osteomalacia
44
Nulojix
Post transplant lymphoproliferative disorder
45
Remicade
heart failure
46
Xiidra
unusual taste
47
Nilandron (nilutamide)
dilsulfuram like rxn, night blindess