ultrafiltration Flashcards
where does ultrafiltration occur
afferent arteriole
why is the afferent arteriole thicker than the efferent arteriole
to create a filtration pressure gradient in the glomerulus to force substances out
why does the glomerulus have a basement membrane
acts as the first filter
what is the function of the basement membrane
has endothelium gaps to allow small substances to pass through, blocks RBC, WBC and large plasma proteins
why does the bowmans capsule wall have podocytes
specialised cells acting as a 2nd filter
how do podocytes act as a 2nd filter
has extensions called pedicels which is a backup system in the occasion that the basement membrane is damaged stopping RBC, WBC and plasma proteins
what happens to the molecules that are too large to pass into the bowmans capsule
they pass through networks of vessels in the glomerulus and then leave via the efferent arteriole
what happens to the substances that were small enough to pass into the bowmans capsule
now called filtrate, the useful substances of the filtrate (glucose, water, vitamins, amino acids, hormones) get reabsorbed