the liver functions Flashcards

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1
Q

what are the three main functions of the liver

A

break down excess amino acids
removes harmful substances
stores glycogen

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2
Q

what is the first step to the liver breaking down excess amino acids

A

nitrogen-containing amine groups are removed from excess amino acids (NH2) forming ammonia and other organic acids

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3
Q

what is it called when ammonia and organic acids are formed from excess amino acids

A

deamination

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4
Q

what are the organic acids produced from deamination used for

A

they are respired to give ATP, or converted to a carbohydrate to be stored as glycogen

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5
Q

why cant we discrete ammonia

A

it is too toxic

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6
Q

how does the liver deal with the toxicity of ammonia

A

it is combined with CO2 to make urea in the ornithine cycle

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7
Q

what is the final stage of the liver breaking down the excess amino acids

A

urea is released from the liver into the blood for the kidneys to filter and turn into urine

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8
Q

what does the liver break alcohol down into

A

ethanal

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9
Q

what does the liver break ethanal into

A

acetic acid

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10
Q

what does excess alcohol in the liver lead to

A

cirrhosis of the liver whereby the cells begin to die

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11
Q

what painkiller does the liver break down and why

A

paracetamol, excess of this can lead to kidney and liver failure

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12
Q

why does the liver break down insulin

A

excess insulin can cause problems with blood sugar levels

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13
Q

how does the liver store glycogen

A

converts excess glucose in the blood into glycogen until it is needed for energy

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