Ulcers Flashcards
occur with greater frequency that other types of peptic ulcers?
duodenal ulcer
onset 20-50 years of age- which ulcer?
duodenal ulcer
positive family history- which ulcer?
duodenal ulcer
cancer risk not increased- which ulcer?
duodenal ulcer
pain 2-3 hours after eating- which ulcer?
duodenal ulcer
what promotes metaplasia in duodenum?
increased duodenal acid
what two things does H. pylori activate?
immune cells and release of inflammatory cytokines
what immune cells are activated in duodenal ulcer?
T and B lymphocytes with infiltration of neutrophils
primary defect is an abnormality that increases the mucosal barrier’s permeability to hydrogen ions- which ulcer?
gastric ulcer
decreased mass of WHAT in gastric ulcer?
decreased mass of parietal cells
what area common for gastric ulcer?
antral area
development of gastric ulcers and may precipitate ulcer formation by limiting the mucosa’s ability to secrete a protective layer of mucous?
chronic gastritis
decreased mucosal synthesis of prostaglandins- which ulcer?
gastric ulcer
damage to mucosal membrane from duodenal reflux of bile and pancreatic enzymes- which ulcer?
gastric ulcer
NSAIDs asociated with which ulcer?
gastric ulcer
what do NSAIDs decrease?
prostaglandin synthesis