Asthma

Question 1

most common type of asthma?

Answer 1

allergic asthma

Question 2

antigen exposure to the bronchial mucosa- initiates airway hyperresponsiveness- which phase of asthma?

Answer 2

early asthmatic response

Question 3

immune activation- which phase of asthma?

Answer 3

early asthmatic response

Question 4

What immunoglobulin is involved in the early asthmatic response?

Answer 4

IgE

Question 5

IgE causes what two things to happen in early asthmatic response?

Answer 5

(1) mast cell degradation and (2) inflammatory mediator release

Question 6

what are the three inflammatory mediators released in the early asthmatic response?

Answer 6

(1) histamine (2) prostaglandins (3) leukotrienes

Question 7

inflammatory mediators in early asthmatic response cause increase or decreased capillary permeability?

Answer 7

increased

Question 8

mucosal edema seen in which phase of asthma?

Answer 8

early asthmatic response

Question 9

bronchial smooth muscle contraction (bronchospasm) is caused by what in the early asthmatic response?

Answer 9

inflammatory mediators

Question 10

tenacious mucous secretion from mucosal goblet cells with narrowing and obstruction to airway- which phase of asthma?

Answer 10

early asthmatic response

Question 11

what cells secrete tenacious mucous in early asthmatic response?

Answer 11

mucosal goblet cells

Question 12

when does late asthmatic response begin?

Answer 12

a few hours after the early response

Question 13

release of toxic neuropeptides contribute to increased bronchial hyperresponsiveness- which phase asthma?

Answer 13

late asthmatic response

Question 14

impaired expiration causes air trapping- which phase of asthma?

Answer 14

late asthmatic response

Question 15

what do toxic neuropeptides contribute to in late asthmatic response?

Answer 15

increased bronchial hyperresponsiveness

Question 16

what causes air trapping in late asthmatic response?

Answer 16

impaired expiration

Question 17

hyperinflation distal to obstructions in late asthmatic response is caused by what?

Answer 17

impaired expiration

Question 18

increased work of breathing seen in which asthma phase?

Answer 18

late asthmatic response

Question 19

respiratory alkalosis seen in which asthma phase?

Answer 19

late asthmatic response

Question 20

what is the acid-base imbalance of late asthmatic response?

Answer 20

respiratory alkalosis

Question 21

increased pH seen in which phase of asthma?

Answer 21

late asthmatic response

Question 22

Ph is increased or decreased in late asthmatic response?

Answer 22

increased

Question 23

PaCO2 is increased or decreased in late asthmatic response?*****

Answer 23

decreased

Question 24

hypoxemia in late asthmatic response further increases WHAT?

Answer 24

hyperventilation

Question 25

bronchospasms become more and more severe- what asthma phase?

Answer 25

status asthmaticus

Question 26

with progressive obstruction of expiratory airflow, air trapping becomes more severe- what asthma phase?

Answer 26

status asthmaticus

Question 27

lungs and thorax become hyperexpanded- what asthma phase?

Answer 27

status asthmaticus

Question 28

fall in tidal volume with increasing CO2 retention- what asthma phase?

Answer 28

status asthmaticus

Question 29

what is the acid-base imbalance seen in status asthmaticus?

Answer 29

respiratory acidosis

Question 30

respiratory acidosis is seen in which asthma phase?

Answer 30

status asthmaticus

Question 31

respiratory acidosis signals what in asthma response?

Answer 31

respiratory failure

Question 32

ventilation is severely impaired, little air exchange is taking place, “silent chest”- which asthma phase?

Answer 32

status asthmaticus

Question 33

tidal volume is increased or decreased in status asthmaticus?

Answer 33

decreased

Question 34

CO2 retention is increased or decreased in status asthmaticus?

Answer 34

increased