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D3 > ÜGE > Flashcards

ÜGE Flashcards

1
Q

PRKAR1A gen mutasyonları nedir ?

A

Bilateral mikronocüler adrenal hiperplazi 10mm den küçük
ACTH bağımsız cushing

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2
Q

Ektopik kortikotropin sendromu en sık nedeni ?

A

Akciğerin küçük hücreli karsinomu

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3
Q

McCune-Albright sendromu ?

A

ACTH bağımsız Cushing sendromu
GNAS mutasyonları ile karakterize multisistemik hastalık

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4
Q

Hipofize bağlı cushing en sık gözlenen değişiklik

A

Crooke hyalin değişikliği

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5
Q

Ön hipofizde ACTH üreten hücrelerin sitoplazmasında ne değişimi olur ?

A

intermediate keratin filamanları birikir.

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6
Q

Diffüz hiperplazi hangi durumda gözlenir ?

A

ACTH bağımlı Cushing sendromunda

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7
Q

Cushing sendromu kliniği

A

Hipertansiyon obezite
yuvarlak yüz
bufalo hörgücü
osteoporez sekonder diyabet
deride hassaslaşma

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8
Q

Spironolakton cisimcikler ?

A

Aldosteron üreten adenomlarda eozinofilik laminer görünümlü sitoplazmik inklüzyonlar

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9
Q
A
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D3 (4 decks)

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