UC and CD Flashcards
clinical features of ulcerative colitis?
> 5 stools a day with high temp and tachycardia
blood in stool
LLQ pain
1st line treatment for single exacerbation of UC?
5-asas (amino salicylates)
E.g mesalazine, sulfasalazine
side effects of 5-asa?
headache, nausea, rash
sensitivity to light
can discolour tears or urine
2nd line treatment for UC?
immunosuppressants
E.g azathioprine, mercaptopurine
cautions of immunosuppressant use?
nausea and vomiting
increased infection risk
flu like symptoms 2-3 weeks after
when to use steroids for uc?
induce remission short term with or in place of 5-asa
side effects of steroids?
acne, weight gain and mood changes
why take steroids in the morning?
prevent night disturbance
alternative treatment for UC?
biologics ( anti TNF-alpha antibodies)
E.g infliximab, adalimumab
side effects of biologics?
increased infection risk
vertigo/dizziness
allergy-like reactions
advice for pregnancy and UC?
doesn’t affect fertility
plan to conceive when well controlled
use folic acid
clinical features of Chron’s?
unexplained persistent diarrhoea 4-6wks
abdominal pain
weight loss
treatment options for CD?
no cure
use of steroids episodically
liquid diet
surgery to remove inflamed section of bowel
routine reviews
lifestyle advice for CD?
encourage smoking cessation
