U3 Homeostasis: Blood glucose regulation Flashcards
What form does sugar in the blood take?
Glucose
Why do cells need a constant supply of glucose?
Glucose is the source of energy for all cells’ activities
Energy is released from cellular respiration:
glucose + O2 → CO2 + H2O + energy
Where does the body get glucose from?
Carbohydrates in our food being broken down into glucose during digestion then being absorbed into the blood through the walls of the small intestine
What is glucose stored as?
Glycogen, a molecule made of long chains of glucose molecules
Glycogenesis
The conversion of glucose into glycogen for storage when stimulated by insulin
Gluconeogenesis
The conversion of fats or amino acids into glucose
Glycogenolysis
The conversion of glycogen into glucose using glucagon
Lipogenesis
The conversion of glucose into extra fats or proteins
Lipolysis
The conversion of extra fats or proteins into glucose
Beta cells and Alpha cells
Beta cells
- secrete insulin to decrease blood glucose level
- glycogenesis (glucose into glycogen)
- lipogenesis (glucose into fat)
- protein synthesis (glucose into protein)
- translocation (glucose transported into body cells)
Alpha cells
- secrete glucagon to increase blood glucose level
- glycogenolysis (glycogen into glucose)
- gluconeogenesis (fats into glucose)
- lipolysis (fats into glucose)
Hepatic portal vein
- Where most of the liver’s blood supply travels through
- Brings blood directly from the stomach, spleen, pancreas and intestines
- Means the liver is the first gland that can absorb the nutrients from digested food
Roles of adrenal glands in regulation of blood glucose level
Adrenal cortex
- Stimulate by secretion of adrenocorticotropic hormone (ACTH) from the anterior pituitary lobe
- Secretes glucocorticoids (eg: cortisol), which:
- regulate carbohydrate metabolism by ensuring enough energy is provided to the cells
- stimulate the conversion of glycogen into glucose during glycogenolysis
Adrenal medulla
- Secretes adrenaline noradrenaline, which:
- increase blood glucose level through glycogenolysis
- stimulate production of lactic acid (which can be converted into glucose in the liver) from glycogen in muscle cells