U3 AOS1 Neurotransmitters and neuromodulators Flashcards
Neuron
an individual
nerve cell that
is specialised to
receive, process
and/or transmit
information
within the
nervous system
Neural
transmission
an electrical
impulse that
occurs when
a neuron is
activated or fires
Neurotransmitter
a chemical
produced
by neurons
that carries
messages to
other neurons or
cells within the
nervous system,
including
muscles, organs
and glands
Synapse
the point of
communication
between two
neurons or
between a
neuron and a
target cell such
as a muscle
or gland
Synaptic vesicle
a membranebound sphere
filled with
neurotransmitter
molecules
Synaptic gap
the space
between the
axon terminal of
the presynaptic
neuron and the
membrane of the
post-synaptic
neuron
Receptor site
a membrane
protein on the
dendrites of
neurons that
receive and
detect specific
neurotransmitters
Excitatory effect
the increased
likelihood that
the post-synaptic
neuron will
fire an action
potential or
neural impulse
Glutamate
the main
excitatory
neurotransmitter
in the nervous
system, which
is involved with
learning and
memory
Inhibitory effect
the decreased
likelihood that
the post-synaptic
neuron will
fire an action
potential or
neural impulse
Gammaaminobutyric
acid (GABA)
the main
inhibitory
neurotransmitter
in the nervous
system,
associated with
anxiety, specific
phobias and
Parkinson’s
disease
Dopamine
a multifunctional
neurotransmitter
with both
excitatory
and inhibitory
effects, that
is involved in
many central
nervous system
functions such
as movement,
pleasure,
attention, mood,
cognition and
motivation
Neuromodulator
a subclass of
neurotransmitters
that alter
the strength
of neural
transmission,
by increasing or
decreasing the
responsiveness
of neurons to
neurotransmitter
signals
Reward pathway
a group of
structures in
the brain that
are activated
by rewarding
or reinforcing
stimuli
Serotonin
an inhibitory
neurotransmitter
that also
acts as a
neuromodulator,
influencing a
variety of brain
activities
Serotonin
pathway
serotonin’s
neuromodulatory
system, which
originates in
the brainstem
and extends to
almost all areas
of the cerebrum
including the
cerebral cortex