U1T2 - Keywords Flashcards
Metabolism
The chemical processes which occur within a living organism to maintain life.
Enzymes
Biological catalysts which speed up reactions in the body without being used up.
Highly substrate specific
Substrate must be complementary to the active site.
Active site
The place where a substrate attaches to on an enzyme.
Complementary
Fits the shape exactly.
Substrate
The molecule an enzyme must catalyse which fits into its active site.
Cofactors
Non protein part of a conjugated protein. Essential for the enzyme to function properly.
Inhibitor
Chemicals which stop or slow down the work of enzymes.
Catabolism
Breakdown of molecules.
Anabolism
Building up of molecules.
Prosthetic groups
Cofactor which is tightly bound permanently to enzyme (usually metal ion)
Coenzymes
Organic molecules which bind temporarily to enzyme.
Lock + Key Model
Active site of enzyme is complementary to substrate shape, products released as they aren’t complementary to active site shape.
Induced Fit Model
Active site of enzyme closely matches shape of substrate but can mould around substrate and so is flexible. It puts pressure on substrate which breaks bonds, lowering activation energy. Products released as they aren’t complementary to active site which then returns to original shape. Only catalyes one substrate.
Activation energy
Minimum amount of energy required to raise substrate molecules to their transition state.
Transition state
The point when molecules react and the products are formed immediately. High energy intermediates (ES)
Enzyme-substrate complex
High energy, unstable intermediates which form momentarily.
Intermediates
Molecular entity formed from reactants to give direct products of reaction.
Enzyme-product complex (EP)
When enzyme and products are together.
Kinetic energy
Energy in motion
Optimum
The best temp/pH/concentration where the rate of reaction Is the highest possible.
Denature
The shape of the active site of the enzyme is changed as a result of hydrogen + ionic bonds being broken in the tertiary structure which is permanent + irreversible.
Limiting factor
A factor in a reaction which will stop the rate increasing further as it is lacking and so the rate levels off.