Typhus Flashcards
1
Q
Typhus
Two types of Typhus in Sri Lanka
A
- Scrub typhus ( Orientia tsutsugamashi)
- Endemic typhus ( Rickettsia typhus)
2
Q
Typhus
Scrub typhus Vector
A
Trombiculid mite
3
Q
Typhus
Endemic typhus vector
A
Rat flea
4
Q
Typhus
Epidemic typhus MO
A
Rickettsia prowazeki
5
Q
Typhus
Epidemic typhus vector
A
human body louse ( rare)
6
Q
Typhus
Ix
A
Clinical. Rx on suspicion. Hard to Dx
7
Q
Typhus
Pathogenesis
A
- Enter into body by tick bite or scratch ( innoculation of tick feces through skin)
- Local lesions - Inflammatory response ( eschar at the bite site, regional lymphadenopathy)
- Becomes generalized ( vasculitis, endovasculitis)
8
Q
Typhus
Eschar
A
brown crusted necrotic painless papule - like a cigarette burn mark
9
Q
Typhus
Endovasculitis causes
A
rash and bleeding diasthesis
10
Q
Typhus
Incubation period
A
2 weeks
11
Q
Typhus
Sx during acute phase
A
- swinging fever
- frontal headache
- myalgia
- conjunctival infection
12
Q
Typhus
Sx progression
A
- Acute phase - abrupt onset fever, myalgia, frontal headache, conjunctival infection
- Towards the end of the first week- generalized lymphadenopathy, meningism, hepatosplenomegaly, rash
- ESCHAR!!!!!!
13
Q
Typhus
Fever +Rash»_space;»
A
Consider typhus and look for an eschar!!!
14
Q
Typhus
Fever + Rash + deafness/ tinnitus»>
A
Typhus?
15
Q
Typhus
Complications
A
- Pulmonary involvement - pneumonia, pleural effusion
- Neuro - various degrees of meningitis, encephalopathy, deafness, tinnitus
