IMN Flashcards

1
Q

IMN

IMN is also known as

A
  • Glandular fever
  • Kissing disease
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2
Q

IMN

MO

A
  • EBV ( HHV- 4)
  • Rarely - CMV ( HHV- 5)
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3
Q

IMN

Most common age group

A
  • adolescents
  • young adults
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4
Q

IMN

Incubation period

A

1-2 months

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5
Q

IMN

Sx

A
  • Fever
  • Headache
  • Malaise
  • Sore throat
  • Palatal petechiae
  • Tonsilar enlargement
  • Cervical lymphadenopathy ( posterior cervical LN)
  • Splenomegaly
  • Mild hepatitis/ jaundice
  • Hemolytic anemia
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6
Q

IMN

Rash?

A

Transient macular rash if taken ampicillin

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7
Q

IMN

Complications

A
  • Myocarditis
  • Meningitis
  • Encephalitis
  • Mesenteric adenitis
  • Splenic rupture ( Rare)
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8
Q

IMN

Why IMN pts are advised against contact sports

A

Risk of splenic rupture

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9
Q

IMN

EBV other manifestations

A
  • Burkitts lymphoma
  • undifferentiated nasopharyngeal CA
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10
Q

IMN

Dx

A
  • FBC- increased WBC (lymphocytes)
  • Activated mononuclear cells ( Activated CD 8+ T cells)
  • Monospot test
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11
Q

IMN

FBC results vary from other viral fevers

A

viral fevers usually have low WBCs, here increased WBCs

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12
Q

IMN

Monospot test

A
  • Confirmatory test
  • detects IgM Ab in the second week
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13
Q

IMN

Rx

A
  • Usually self- resolving
  • Steroids if neuro Sx (encephalitis, meningitis, GBS) or if reduced plts, airway obstruction due to tonsil enlargement or hemolysis
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14
Q

IMN

When is steroids given

A
  • Neuro involvement ( Encephalitis, meningitis, GBS)
  • Hemolysis
  • Marked thrombocytopenia
  • Tonsilar enlargement
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15
Q

IMN

Risk of tonsilar enlargement

A

airway obstruction

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16
Q

IMN

FBC- lymphocytes finding

A

50% lymphocytes w at least 10% atypical lymphocytes

17
Q

IMN

Hemolytic anemia is warm or cold

A

cold