Types of insulin

Question 1

What insulins are very rapid acting analogs?

Answer 1

Aspart (Fiasp) and Lispro-aabc (Lyumjev)

Question 2

What insulins are rapid acting analogs?

Answer 2

Aspart (Novolog), Lispro (Humalog/Admelog), and Glulisine (Apidra).

Question 3

What is short acting insulin?

Answer 3

Regular

Question 4

What is intermediate acting insulin?

Answer 4

NPH

Question 5

What are types of long acting insulin?

Answer 5

Detemir (Levemir), Glargine (Lantus, Basaglar, Semglee, Rezvoglar), and Degludec (Tresiba).

Question 6

What insulins are basal + bolus

Answer 6

Intermediate + short - combo of NPH + regular
70/30 = 70% NPH + 30% Regular
50/50 = 50% NPH + 50% Regular

Intermediate + rapid
Novolog Mix - 70/30
Humalog Mix - 75/25 or 50/50

Question 7

What is the onset, effective peak and duration for very rapid acting analogs of insulin?

Answer 7

Onset is 16-20 minutes
Effective peak is 1-3 hours
Duration is 5-7 hours

Question 8

What is the onset, effective peak and duration for rapid acting analogs of insulin?

Answer 8

Onset is 15-30 minutes
Effective peak is 1-3 hours
Duration is 3-7 hours

Question 9

What is the onset, effective peak and duration for short acting insulin?

Answer 9

Onset is 30-60 minutes
Effective peak is 2-4 hours
Duration is 5-8 hours

Question 10

What is the onset, effective peak and duration for intermediate acting insulin?

Answer 10

Onset is 2-4 hours
Effective peak is 4-10 hours
Duration is 10-16 hours

Question 11

What is the onset, effective peak and duration for long acting insulin?

Answer 11

Long acting insulin doesn’t have a peak

Detemir (Levemir)
Onset is 3-8 hours
Duration is 6-24 hours

Glargine (Lantus/Basaglar/Semglee/Rezvoglar)
Onset 2-4 hours
Duration 20-24 hours

Degludec (Tresiba)
Onset ~1 hour
Duration less than 42 hours

Question 12

What is the onset, effective peak and duration for NPH + regular insulin?

Answer 12

Onset 30-60 minutes
Dual peaks
Duration 10-16 hours

Question 13

What is the onset, effective peak and duration for Novolog and Humalog mix insulin?

Answer 13

Onset 5-15 minutes
Dual peaks
Duration 24 hours

Question 14

What blood glucose does bolus insulin decrease? What reflects the efficacy?

Answer 14

Bolus insulin lowers after meal blood glucose. Post meal blood glucose reflects efficacy.

Question 15

What blood glucose does basal insulin decrease? What reflects the efficacy?

Answer 15

Basal insulin controls blood glucose between meals and nighttime. Fasting blood glucose reflects efficacy.

Question 16

What are side effects of insulin?

Answer 16

Hypoglycemia and weight gain

Question 17

What is the typical dosing range of insulin?

Answer 17

0.5-1 units/kg of body weight/day