Types and Function of Neuroglia Flashcards
Ependymal Cells
-lines the ventricles of the brain
-help circulate the cerebral spinal fluid
Astrocytes
-found in the CNS;
-provide structural matrix for neurons,
-play major homeostatic role for neurons- regular extracellular potassium and involved in recycling certain neurotransmitter substances following release
Olgiodendrocytes
-Found in the CNS;
-form and maintain myelin,
-maintains functional integrity of paranodal region,
-enables saltatory conduction
Microglia
-numerous distributed,
-following injury microglia become macrophages which clear out debris,
-mediate immune response
Satellite Cells
-modulate the PNS following injury and inflammation,
-assist in regulating the external chemical environment
Schwann Cells
-Found in the PNS
-same function as Oligodendrocytes- form and maintain myelin, maintains functional integrity of paranodal region, enables saltatory conduction
Synaptic Pruning
- Experience and use
- Eliminates weaker synaptic contacts while stronger connections are kept and strengthened
- Based on neuronal use
Neuronal Impulse
-Jumping from node to node to exchange sodium and potassium
-Nodes of Ranvier = Salatory transmission
-Action potential: dendrite, cell body, axon hillock
- Saltatory Conduction = neural impulses jumping from node to node
Myelinization
-want myelin
-want a large diameter
- conduction velocity = greatest impact on myelin
Neural Response to Injury
-Neuroplasticity: brain’s ability to change as a result of experience
-Generate a different pathway
-use it or lose it
-Neuroglial: immediate response to get rid of debris
o Phagocyte activity