Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Immunology Block 3 > Type 4 Hypersensitivities (Autoimmune Diseases) > Flashcards

Type 4 Hypersensitivities (Autoimmune Diseases) Flashcards

1
Q

What is the self antibody being made in Scleroderma?

A

Scl-70

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Autoantibodies will attack what in Scleroderma?

A

topoisomerase 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are 2 important signs in Scleroderma?

A

Raynauds phenomena

sclerodactyly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Autoantibodies are being made against what in CREST?

A

anti-centromere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how do you differentiate between CREST and Scleroderma?

A

CREST has Raynauds and sclerodactyly but additionally has telangiactasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the autoantibodies in SLE?

A

anti-dsDNA

anti-Smith

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the 4 symptoms in SLE?

A
  1. Malar rash
  2. photosensitivity
  3. oral ulcer
  4. arthritis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what drug induces lupus?

A

isoniazid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

drug induced lupus makes autoantibodies against what?

A

anti-histones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the autoantibodies made in Sjorgren?

A

anti-ro

anti-la

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what symptom is seen in Sjogren/s disease?

A

dryness in eyes and mouth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what will be infiltrated by antibodies?

A

exocrine glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Sjogren disease patients have higher risk of this cancer:

A

malignant lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Grave’s disease is an example of what disease?

A

hyperthyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the most common cause of Myasthenia Gravis?

A

abnormal thymus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

in multiple sclerosis, you make autoantibodies against what?

A

anti-myelin

17
Q

what 2 symptoms are seen in Multiple Sclerosis?

A

nystagmus and dysarthria

18
Q

what happens in rheumatoid arthritis?

A

autoreactive T helper 2 cells recruit and activate macrophages that release inflammatory cytokines.

The cytokines activate RANK which releases MMP, these degrade bone

19
Q

what antibody is seen in rheumatoid factor?

A

IgM

20
Q

rheumatoid factor destroy’s what?

A

Fc part of IgG

Immunology Block 3 (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions