AIDS Flashcards
1
Q
what cells will be destroyed in AIDS?
A
CD4+ T cells
2
Q
what causes AIDS?
A
HIV
3
Q
what kind of virus is HIV?
A
retrovirus
4
Q
what are the 2 membrane phospholipids found in HIV?
A
1) GP 41
2) GP 120
5
Q
What are the 3 HIV receptors on the host cell? and which cells have each?
A
1) CXCR4 –> T cells
2) CCR5 –> Macrophages
3) CD4 –> Tcells
6
Q
the GP 120 phospholipid of HIV will bind mostly to what host receptor?
A
CXCR4
7
Q
Why is it so difficult to eliminate the HIV virus?
A
because it integrates into the host DNA and can remain latent for years
8
Q
what happens if a person has a mutation in CCR5 while having HIV? what cells will have this mutation?
A
they may remain disease free for years if macrophages have the mutation
9
Q
Levels of CD4+ that fall below that number indicate HIV?
A
below 200
