Type 3 Hypersensitivity Flashcards
1
Q
Mixed essential cryoglobulinaemia is associated with?
A
Hep C
2
Q
Rash, itching, joint pain, LN, and fever 7-12 days after taking penicillin (antiserum)
A
Serum sickness
3
Q
How is serum sickness diagnosed?
A
Low C3
4
Q
Associated with Hep B, pericarditis and MI
Rosary sign
A
Polyarterits nodosa (Med vessel vasculitis)
5
Q
Main antibodies in SLE?
A
ANA
Anti-dsDNA
Also anti histone, anti sm, anti U1RNP
6
Q
SLE more common males or females?
A
9x more common in females
7
Q
Symptoms of SLE?
A
Serositis Seizure Aphthous ulcers Arthritis Photo sensitivity Malar rash Discoid rash Haem: AIHA, low plts Kidney probs
8
Q
4 extractable nuclear antibodies?
A
Ro
La
Sm
U1RNP
9
Q
What is the underlying process in type 3 hs?
A
Deposition of immune complexes causes tissue damage
Rash
Arthritis
Glomerulonephritis
