Type 2 diabetes Flashcards
What is type 2 diabetes?
A chronic condition involving insulin resistance and sometimes an insulin secretory defect
What is the genetic change that offspring of T2DM patients will also develop diabetes?
40%
What is insulin resistance associated with?
Hypertension
Hyperlipedaemia
Hyperglycaemia
Polycystic ovarian syndrome
What are the symptoms of type 2 diabetes?
Fatigue
Blurred vision
Polyuria
Recurrent UTIs
Which patients typically present with type 2 diabetes?
Overweight/obese
Middle aged/elderly
Strong family history
Inactive
What is the initial management for type 2 diabetes?
Lifestyle change:
Aim to lose 5-10kg per year to reduce complications
Change in diet and introduction of exercise
When is a sulphonylurea used as the first stage management in type 2 diabetes?
In patients who are not overweight
In patients who are intolerant to metformin
When can thiazolidinediones be added into therapy?
Added as combination therapy to metformin and sulphonylurea therapy
As monotherapy if intolerant to both
In which patients should pioglitazone not be prescribed?
Heart failure
