type 1 & 2 diabetes Flashcards
type 1 symptoms (4T’s)
toilet, thirsty, tired, thinner
type 2 symptoms
increase eps of genital thrush, slow wound healing
type 2 risk factors
ethnicity, age, obesity, genetics, smoking, alcohol, increased bp, pcos, poor sleep
1st choice oral therapy
metformin
disadvantage of sulfonylureas
can cause hypos
moa of sulfonylureas
enhance insulin secretions
which drug reduces peripheral insulin resistance
pioglitazone
Moa of dpp-4 inhibitors
reduce hepatic glucose output and enhance incretin action
disadvantage of dpp-4 inhibitors
not as effective
which 2 drugs can be used in renal impairment
pioglitazone, dpp-4 inhibitors
which 2 drugs cause weight loss
SGLT-2 inhibitors, GLP-1
moa of SGLT-2 inhibitors
reduce reuptake from glomerular filtrate
formulation of GLP-1
injecion
metformin moa
reduce peripheral insulin resistance, reduce hepatic glucose output
