Tylenol/ Acetamphen Flashcards
0
Q
Mech of action
A
COX inhibitor>elevation of pain threshold, antipyretic by acton on hypothalmic heat regulatory center
1
Q
Drug class
A
Antipyretic/ Analgesic
2
Q
Pharmacokinetics
A
OOA - 15-30min
Peak - 30-120min
Duration - 3-4hrs
HL - 1-3hrs
3
Q
Indications
A
Pediatric fever
4
Q
Contraindications
A
Hypersensitivity
5
Q
Side effects
A
Dizzy, abdominal pain, hypoglycemia, N/V
6
Q
Dose
A
PEDI - 15 mg/kg PO Q4-6HR PRN max dose 4g/day
7
Q
Precautions
A
Metabolized by liver - overdose can be toxic
Does not have anti-platelet aggregation effect
Does not have peripheral anti-inflammatory effect
8
Q
Drug - Drug
A
Chronic excessive use of alcohol increases risk of hepatoxicity