Tylenol/ Acetamphen Flashcards

0
Q

Mech of action

A

COX inhibitor>elevation of pain threshold, antipyretic by acton on hypothalmic heat regulatory center

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1
Q

Drug class

A

Antipyretic/ Analgesic

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2
Q

Pharmacokinetics

A

OOA - 15-30min
Peak - 30-120min
Duration - 3-4hrs
HL - 1-3hrs

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3
Q

Indications

A

Pediatric fever

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4
Q

Contraindications

A

Hypersensitivity

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5
Q

Side effects

A

Dizzy, abdominal pain, hypoglycemia, N/V

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6
Q

Dose

A

PEDI - 15 mg/kg PO Q4-6HR PRN max dose 4g/day

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7
Q

Precautions

A

Metabolized by liver - overdose can be toxic
Does not have anti-platelet aggregation effect
Does not have peripheral anti-inflammatory effect

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8
Q

Drug - Drug

A

Chronic excessive use of alcohol increases risk of hepatoxicity

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