Tx for VTE

Question 1

Tx for provoked VTE

Answer 1

1. LMWH atleast 5 days

or

INR > 2 for 24 hours

( continue for 3 months )

2. VKA within 24 hours and continued for 3 months

Question 2

Tx for unprovoked VTE

Answer 2

1. LMWH for atleast 5 days or INR > 2 for 24+ hours
2. VKA for 24 hours and continued for 3 months
3. Assess risks and benefits of continuing anticoag for VTE prevention

Question 3

VTE in patients with active cancer

Answer 3

1. LWMH for 6 months

2. Reassess for continued treatment

Question 4

Mx of confirmed PE or proximal DVT

Answer 4

1. Offer LWMH or fondaparinux asap unless
   - severe renal impairment
   - increased risk of bleeding
   - haemodynamically unstable
2. Offer a VKA (e.g. warfarin) to patients with confirmed proximal DVT or PE within 24 hours of diagnosis and continue warfarin for atleast 3 months

Question 5

Mx of confirmed PE or proximal DVT and active cancer

Answer 5

Offer LMWH and continue for 6 months