Tx: Complications in Pregnancy Flashcards
Anemia
- iron deficiency, severe, prevention
- Iron deficiency: eat meat, leafy greens. Acidic foods to increase absorption. Iron supplements
- Avoid tea, phytates, alkalines, tetracyclines
- Blood transfusion if severe - shock, heart failure
- Prevention:
- Screening
- Iron and folate supplements
- Treat infections
- Family planning
Placenta previa
*3rd trimester*
Consult OB
- Admit
- Stabilize
- Magnesium sulfate
Management determined by state of mom & fetus
- Delivery:
- nonreassuring fetal HR
- life-threatening maternal hemorrhage,
- >34 weeks + known fetal lung maturity
- Delivery when stable
Placental abruption
*3rd trimester*
- C/S if maternal or fetal jeopardy
- Vaginal delivery if term, in labor, and mom & fetus are stable
- Conservative tx in hospital if preterm, contractions have stopped, and mom & fetus are stable
- Rh (-): RhoGam
- Hospitalized remainder of pregnancy, tx depends on size of the abruption
- May need immediate delivery and stabilization
Vasa previa
*3rd trimester*
Immediate C/S
Uterine rupture (6)
*usually labor*
- Immediate C/S
- Left lateral decubitus position (maintain blood flow to fetus)
- D/C pitocin
- O2
- SQ terbutaline
- Emergency laparotomy if other measures fail
Cervical insufficiency (incompetent cervix)
*2nd Trimester*
- Cerclage (12-14 weeks if ≥2 prior 2nd trimester losses or ≥3 preterm births)
- US surveillance beginning at 14-16 weeks → cerclage if necessary
- Hydroxyprogesterone caproate prophylaxis with singleton until 36 weeks
- Alt: vaginal progesterone, pessary
Chronix/Pre-existing HTN
- A-methyldopa
- Labetolol
- Nifedipine
Preeclampsia
Resolves after delivery of placenta.
Severe:
- Delivery at 34 weeks
- Admit
- Betamethasone
- Antihypertensives
- IV magnesium sulfate
If <33-37 weeks give steroids, don’t delay delivery beyond maternal stabilization (when in doubt, deliver).
Postpartum HTN
>150/100
- Labetolol
- Nifedipine
- or both
- f/u in 3 days
Eclampsia
- MgSO4 IV
- watch for Mg toxicity, treat with calcium gluconate
HELLP Syndrome
Same management as preeclampsia if HTN present.
- Delivery at 34 weeks
- Admit
- Betamethasone
- Antihypertensives
- IV magnesium sulfate
Goal is delivery
Gestational DM Tx
- A-1: diet controlled
- A-2: insulin or oral meds
- metformin, glyburide, insulin if FBG >110
- Diet and exercise modification for everyone
- Encourage breastfeeding after delivery for glycemic control
Gestational DM Goals
Goal is strict euglycemia
- Fasting <95
- 1h Postprandial <140
- 2h Postprandial <120
Gestational DM Delivery
- A-1: Up to 41 weeks
- A-2: up to 39 weeks
Rh Alloimmunization
Prevention: RhoGam 300mg IM
- 28 weeks
- within 72 hours of delivery
If alloimmunization has occurred:
- Deliver at 37 weeks
- Future pregnancies with IVF, sperm donation, or surrogacy
Hydrops fetalis
fatal
Breech presentation
- Close monitoring
- Breech at 37 weeks: ECV
- Failed ECV/not candidate: C/S at 29 weeks or later (85%)
Indications for C/S (12)
- Dystocia
- Repeat C/S
- Fetal distress
- Malpresentation (breech)
- Placenta previa
- Placenta abruption
- Preeclampsia/eclampsia
- Macrosomia
- Cervical cancer
- Active genital herpes
- Maternal request
- Fetal abnormalities (hydrocephalus)
Reasons to do a repeat C/S
- >1 transverse C/S
- Small pelvis
- Hx of vertical uterine incision
- Hx of myomectomy
C/S incisions
- Midline vertical incision: if emergent C/S
- Transverse (Pfannenstiel) incision: preferred method
- Inpt 3-4 days postprocedure
Dystocia
C/S
Fetal distress
- Turn mother on side (left lateral decubitous)
- O2
- Correct hypotension
- D/C oxytocin
- Exam: check for cord prolapse
Chorioamnionitis
- Close monitoring
- C/S if delivery is not imminent
Amniotic fluid embolism (in mom)
*result from C/S or precipitous labor*
- immediate resuscitation
Peripartum hysterectomy
Total or supracervical approach
Shoulder dystocia
*ACUTE EMERGENCY*
- McRoberts maneuver (maternal legs hyperflexed onto abdomen)
- Wood’s corkscrew maneuver
- Episiotomy
- C/S (suggested for future pregnancies)
Umbilical cord prolapse
- overt, funic, occult
- Overt: EMERGENCY
- Stat pelvic exam - check cervix and check cord pulsations
- Knee-chest position (McRoberts maneuver)
- Continuous upward pressure on fetal presenting part (prevents cord compression)
- O2
- Emergent C/S
- Funic: C/S prior to ROM
- Occult:
- Change pt position
- O2
- Monitor closely
- C/S if compression
Ectopic pregnancy
- OB consult
- Hemodynamically unstable: get to OR
- Hemodynamically stable & ectopic <3.5cm, b-hCG <5000, & not breastfeeding:
- Methotrexate IM
- Rh (-): RhoGam
- Laparoscopy or surgery if not candidate for methotrexate
- Expectant management
Threatened abortion
- Send home
- Nothing per vagina (tampons, intercourse)
Missed abortion
- Misoprostol
- D&C
- Rh (-): RhoGam
- Pelvic rest for 2 weeks
Incomplete/inevitable abortion
- prompt D&C (stop bleeding and prevent infection)
- Rh (-): RhoGam
- Pelvic rest for 2 weeks
Complete abortion
- D&C
- f/u
- Rh (-): RhoGam
- Pelvic rest for 2 weeks
Nonviable fetus
- Admit or D&C
- F/u in 1 week
- Return if heavy bleeding, pain, or fever
- Rh (-): RhoGam
- Pelvic rest for 2 weeks
Septic post-abortion
- Admit
- Fluids
- Abx
Postpartum hemorrhage
- med, stage 0-III
*EMERGENCY - CALL OB*
- Misoprostol
- Stage 0: uterine massage, oxytocin IV
- Stage I: 1 IVs, Methergine, type & match, IV fluids
- Stage II: Prostaglandins, RBC transfusion, consider OR/Epidural
- Stage III: massive transfusion protocol, laparotomy, hysterectomy, uterine artery embolization
Postpartum endometritis
- Call OB
- Broad spectrum abx
- clindamycin + gentamicin or ampicillin + gentamicin if vaginal delivery
Premature Rupture of Membranes (PROM)
- Call OB
- Admit for delivery
- Expectant management
- betamethasone (corticosteroids)
- Abx to prevent strep B infection
- activity restriction
- Removal of cerclage
- Try to manage until 34 weeks
- Prophylactic abx
Preterm Premature Rupture of Membranes (PPROM)
- No sign of fetal distress: admit, fetal monitoring, wait for spontaneous labor
- <34 weeks: betamethasone
- Tocolytics
- Abx: Ampicillin + Azithromycin
- Maternal or fetal distress: Prompt delivery
Premature labor
- Call OB
- Tocolytics to suppres contractions
- Terbutaline
- Magnesium sulfate
- Antenatal corticosteroids = betamethasone
- Abx prophylaxis
Placenta accreta
- C/S, leave placenta for later D&C
- consider Hysterectomy
Gestational Trophoblastic Disease
- D&C with pathology
- Hysterectomy if done having kids
- Follow weekly b-hCG for 3 weeks, then monthly for 3-6 months (make sure trending down)
- if not trending down → malignant → methotrexate and chemo
- Use contraception and do not get pregnant for 6 months (allows us to follow b-hCG to r/o malignancy)
Recurrent Pregnancy Loss
- Low weight molecular heparin (LWMH) /Lovenox
- Aspirin
- IVIg
- Corticosteroids
- Prophylactic heparin and ASA if antiphospholipid antibody syndrome
Induced abortion
- Counseling and informed consent
- Discuss future contraception
- <10-11 weeks: Misoprostol
- Surgery
Baby blues
- Resolve within 2 weeks
- Consider counseling/therapist
Postpartum depression
- CBT 1st line
- Antidepressants
- sertraline if breastfeeding
- Paroxetine
- Refractory: consider ECT (safe during breastfeeding)
- Prophylactic antidepressants if hx of MDD
Postpartum psychosis
- Immediate referral to ED and mental health specialist
Multiple gestation delivery
- Adequate staff - extra nurses, anesthesia, peds, neonatologist
- Fetal monitoring
- Pain control: epidural
- Informed consent if need for C/S
- IV access
- Pitocin
- Aggressive management of 3rd stage of labor (delivery of placenta)