Tutorial 2 - Neurohypophysial Axis Flashcards
During a water deprivation test, what would you expect to happen to the osmolality of the urine? Why?
It should INCREASE because…
When deprived from drinking water, more ADH is released.
ADH puts more aquaporins into the kidney so MORE water is reabsorbed.
Less water in urine so urine is more concentrated.
What is the name for needing to urinate frequently?
Polyuria
What is the name for being thirsty all the time?
Polydipsia
What is DDAVP?
A modified form of vasopressin (anti-diuretic hormone)
What does ADH do?
Causes more water to be reabsorbed.
What are the 2 types of diabetes insipidus?
Cranial - No ADH is produced or released
Nephrogenic - No response to the ADH that is released.
What does diabetes insipidus mean?
Relating to ADH
What could cause Cranial diabetes insipidus?
No ADH is produced so…
- Head injury
- Infection
- Tumour
- Inflammation (hypophyicitis)
- Autoimmune disease
What test could you do to see if someone has an inflamed pituitary/tumour?
Pituitary MRI scan
