Tutorial 2 Flashcards
1
Q
What are examples of:
- Level 1 evidence
- Level 2 evidence
- Level 3 evidence
- Level 4 evidence
- Level 5 evidence
- Level 6 evidence
- Level 7 evidence
A
- Evidence is information of facts obtained systematically using valid methods
- Systematic review of all relevant RCTs (3 or more good quality)
- Evidence from one good quality RCT
- Evidence from well-designed controlled trial without randomisation
- Evidence from well-designed case-control cohort studies
- Evidence from systematic reviews of descriptive and qualitiative studies
- Evidence from single descriptive of qualitative study
- Evidence from authority/expert committee reports
2
Q
What are 5 principles for researching barriers to change?
A
- Acceptibility
- Accuracy
- Generalisability
- Reliability
- Cost-effectiveness
3
Q
What is research translation?
A
- The process by which knowledge is translated into changes in practice or policy
- Needed as research does not always lead to implementation or better health outcomes
- Reduce waste in research
4
Q
What is translational research?
A
- Research that studies how to best translate research into practice or policy
5
Q
What is reliability?
A
- The consistency and trustworthiness of a test measurement
6
Q
What is precision?
A
- Measuring device reliably gives results with little variation
7
Q
What is validity?
A
- Refers to whether the experiment/test measures what it is meant to measure
8
Q
What is content validity?
A
- Established by reviewing the content of assessment procedures
- Face-validity: does the test measure what it is supposed to measure?
- Content scope validity: does the test measure the breadth/depth of an intended construct
9
Q
Which is criterion validity?
A
- Established by reviewing performance of measurements when compared to an external standard
- Concurrent validity = compares to gold standard
- Predictive validity = do the test results successfully predict an outcome
- Known/extreme groups validity = does the test differentiate between groups who should score high or low
10
Q
What is responsiveness?
A
- Refers to how sensitive the test is to real change
11
Q
What are some registered health professions?
A
- Doctors
- Registered nurses
- Pharamacists
- Physiotherapists
- OTs
- Optometrist
- Chiropracter
- Traditional Chinese medicine/acuptuncturist
12
Q
What are some substances regulated by the TGA?
A
- Prescription medicines
- Vaccines
- Sunscreens
- Vitamins and minerals
- Medical devices
- Blood and blood products
13
Q
What are means of improving validity of interviews?
A
- Triangulatioon
- Saturation
- Member checking e.g. Delphi method
- Self-disclosure
14
Q
What is a non-inferiority trial and why are they done?
A
- A non-inferiority trial aims to prove that a drug/dose renders outcomes that are not worse than the gold standard treatment
- Reasons include:
- Not ethical to test against placebo
- New drug has better performance of secondary end points/cheaper/better compliance
15
Q
What is an equivalence trial and why are they done?
A
- Aims to prove that a new drug is no worse, or better than the existing drug
- Needs establishment of equivelant boundary first