Tutorial 1

Question 1

Q: What are the genetic causes of short stature? (3)

Answer 1

A: -turners

• downs
• achondroplasia (causes disproportionate dwarfism)

Question 2

Q: What are the non genetic reasons for short stature? (4)

Answer 2

A: -cushings= excess cortisol

• vitamin D deficiency
• hypothyroidism
• osteochondrodysplasia (bone abnormality)

Question 3

Q: What causes the release of GH?

Answer 3

A: -stress eg vigorous exercise

• sleep
• marmite (due to huge aa load)

Question 4

Q: Describe 2 tests for GH stimulation.

Answer 4

A: in hospital:

• make their blood sugar drop= causes ‘stress’ in body
• check GH levels

insulin tolerance test:

• measure blood GH before and after giving insulin
• GH levels should rise at least to 20mU/L or more
• if less= issues with GH