Tumour Markers/Cancer Genetics Flashcards

1
Q

Ca 125

A

Ovarian

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2
Q

Ca 19 9

A

Pancreatic

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3
Q

Ca 15 3

A

Breast

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4
Q

PSA

A

Prostate

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5
Q

AFP

A

HCC, teratoma

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6
Q

CEA

A

Colorectal

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7
Q

S100

A

Melanoma, Schwannoma

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8
Q

Bombesin

A

SCLC, gastric, neuroblastoma

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9
Q

Philadelphia chromosons

A

T(9:22)
Poor prognostic factor in ALL

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10
Q

Good prognosis ALL

A

FAB L1 type
Common ALL
Pre b phenotype
Low initial WCC
Del9p

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11
Q

Poor prognosis ALL

A

Fab L3
T/B cell markers
Philadelphia
Age not between 2-10
Male
CNS involvement
High initial WBC
Not Caucasian

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12
Q

Burkitt’s lymphoma

A

T(8:14)

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13
Q

Mantle cell lymphoma

A

T(11:14)

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14
Q

Follicular lymphkma

A

T(14:18)

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15
Q

Chronic myeloid leukemia

A

T(9:22)

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16
Q

HCG

A

Seminomas, choriocarcinomas