Tumour markers

Question 1

α-Fetoprotein (AFP) associated tumours?

Answer 1

HCC,

non-seminomatous germ cell tumours of the gonads

Question 2

β-Human chorionic gonadotrophin (β-hCG) associated tumours?

Answer 2

Choriocarcinomas
Germ cell tumours (testicular)
lung cancer

Question 3

Prostate-specific antigen (PSA) associated tumours?

Answer 3

prostate

Question 4

Carcinoembryonic antigen (CEA) associated tumours?

Answer 4

Colorectal Cancer

gastric carcinoma, 
pancreatic carcinoma, 
lung carcinoma, 
breast carcinoma,
medullary thyroid carcinoma, 

non-neoplastic conditions like:
ulcerative colitis, Crohn’s
pancreatitis, 
cirrhosis,
COPD, hypothyroidism
smokers

Question 5

CA125 associated tumours?

Answer 5

Ovarian Cancer

Question 6

CA19–9 associated tumours?

Answer 6

Gastro-intestinal tumours (pancreatic cancer in particular)

Question 7

CA15–3 associated tumours?

Answer 7

Breast Cancer

Question 8

Osteopontin associated tumours?

Answer 8

Many cancers

mesothelioma

Question 9

Calcitonin associated tumours?

Answer 9

Medullary Carcinoma of the throid

Question 10

Thyroglobulin associated tumours?

Answer 10

Papillary and follicular carcinoma

Question 11

What does AFP (in cancer) stand for?

Answer 11

alpha fetoprotein

Question 12

What does CEA (in cancer) stand for?

Answer 12

Carcinoembryonic antigen