tumors/infection Flashcards

1
Q

onion skinning

A

ewings sarcoma

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2
Q

most common primary malignant bone tumor

A

multiple myeloma

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3
Q

ewings sarcoma

A

primary sarcoma found in ages 5-25, in diaphyses of long bones, ribs, and flat bones.

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4
Q

osteosarcoma age and location

A

ages 10-20 yrs old, arising in metaphyseal area of long bones

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5
Q

tumor in metaphyseal area of long bones

A

osteosarcoma

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6
Q

tumor in diaphyses of long bones, ribs, flat bones

A

ewings sarcoma

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7
Q

what enzymes are elevated when the bone is broken down and remodeled

A

alkaline phosphatase and lactate dehydrogenase

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8
Q

what can detect the specific abnormal globulin of multiple myeloma

A

serum and urine protein electrophoresis

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9
Q

soap bubble

A

giant cell tumor

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10
Q

acute hematogenous osteomyelitis of bone affects what

A

long bones in children

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11
Q

pts with sickle cell anemia at risk for what

A

salmonella osteomyelitis

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12
Q

test to order for osteoporosis

A

dual energy xray absorptiometry

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13
Q

exogenous osteomyelitits results from what

A

open fracture and surgery

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14
Q

s/s of acute hematogenous osteomyelitits

A

pain, LROM, soft tissue swelling

drainage rare

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15
Q

s/s of chronic hematogenous osteomyelitits

A

recurrent flare ups of tender, warm, sometimes swollen areas occur, and pts often complain of malaise, anorexia, fever, wt loss, night sweats

as well as pain and drainage from a sinus tract

bone necrosis, soft tissue damage, bone instability

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16
Q

xray changes of osteomyelitits lags by how many days

17
Q

what test is useful for early detection of acute osteomyelitis

A

ultrasonography

18
Q

involucrum

A

periosteal new bone

19
Q

late sequestra(dead bone surrounding granuation tissue) and involucrum take how long to appear

A

few weeks to months

20
Q

acute osteomyelitis tx

A

6-8 weeks of antibiotics- IV or oral

21
Q

chronic osteomyelitis tx

A

4-24 weeks of IV or po antibiotics

22
Q

carcinomas of what are the primary carcinomas that most commonly metastasize to the bone

A

prostate, breast, lung, kidney, thyroid

23
Q

most common site of bony mets

24
Q

in adults over 60 y/o or older, what is the most common source of the bone lesion

A

metastatic carcinoma

25
chondrosarcoma increase in incidence in who and present where
adults older than 60 years or older and can present within the central metaphyseal area
26
incidence of of benign tumors of bone/soft tissue compared to primary malignant tumors
benign tumors of bone/soft tissue more common
27
most common primary benign bone neoplasm of the hand
enchodroma(cartilaginous tumor)
28
ganglions descriptions and appear where
soft, nontender, transilluminate mass dorsum of hand or wrist
29
mucous cysts are ganglia originating where
from the DIP joint and often associated with heberden nodules
30
soft tissue sarcomas incidence compared to primary bone malignancies
3 times
31
most common types of primary sarcomas of bone are...
chondrosarcoma, ewing sarcoma, osteosarcoma
32
pain with malignancy?
painful mass attached to bone is usually malignant
33
severe pain preceded by dull, aching pain
pathologic fracture
34
with neoplasms, what labs are elevated when bone is broken down and remodeled
alk phos and LDH
35
soft tissue sarcoma tx
radiation therapy followed by local resection
36
codman triangle sunburst pattern
periosteal new bone formation at diaphyseal end of lesion osteosarcoma
37
X-ray ## Footnote Lytic lesions are areas of the bone which appear to be eaten away. Describe the appearane Sunburst lesion on x-ray
X-ray ## Footnote Lytic lesions are areas of the bone which appear to be eaten away. They may have sharp edges and no clear border. Sunburst lesion on x-ray = osteosarcoma or ewing’s sarcoma
38
The most common primary malignancies which metastasize to the bone are (3). Bone is the ___ most common area for metastasis Osteosarcomas occur most commonly between the ages \_\_\_\_\_
prostate lung breast 3rd 10 to 20
39
Sarcoma
Sarcoma = cancer of cells which are mesenchymal in origin including bone, fat and vascular cancers. Breast, lung and colon cancer originate from epithelial cells and are usually carcinomas