Tumors and Neurocutaneous Syndromes Flashcards
UMN vs LMN
Muscle Tone: Normal to increased
Upper Motor Neuron Lesion
Neurocutaneous Syndrome seen often with cutaneous lesions,
subependymal nodules
Tuberous Sclerosis
10% of brain tumors
Schwannomas
Neurocutaneous Syndrome retinal angiomas,
cerebellar hemangioblastomas
Von Hippel landau
Glial tumors seen in both children and adults
Children (4th ventricle)
Adults (spinal cord: lumbosacral region)
Ependymoma
UMN vs LMN Lesion
Muscle Atrophy: Early (Denervation)
Muscle wasting
Lower Motor Neuron Lesion
UMN or LMN Lesion
Withdrawal reflexes: Normal
Upper Motor Neuron Lesion
UMN or LMN Lesion
Withdwaral reflexes: Normal
Upper Motor Neuron Lesion
UMN or LMN Lesion
Muscle Atrophy: Late (Disuse)
Upper Motor Neuron Lesion
A clinically agressive brain tumor
Glioblastoma Multiforme
UMN or LMN Lesion
Withdwaral reflexes: Normal
Upper Motor Neuron Lesion
Seen often with neurofibromas and café au lait spots
Neurofibromatosis 1
a.k.a. Von
Recklinghausens disease)-
Seen often with bilateral
acoustic schwannomas, cataracts, deafness
Neurofibromatosis 2
UMN or LMN Lesion
Bladder: Large, Turgid, Difficult to express
Upper Motor Neuron Lesion
UMN or LMN Lesion
Postural Reaction: Delayed to absent
Lower Motor Neuron Lesion
UMN or LMN Lesion
Muscle Tone: Normal (to decreased)
Upper Motor Neuron Lesion
more benign; chiefly
supratentorial , more responsive to treatment
Oligodendroglioma
UMN or LMN Lesion
Withdwaral reflexes: Normal
Upper Motor Neuron Lesion
UMN vs LMN
Bladder: Large, Flaccid, Easy to Express
Lower Motor Neuron Lesion
Often seen at the posterior fossa, and known most frequent
malignant brain tumor in children
Medulloblastoma/ primitive Neuroectodermal
tumor (PNET)
Most common primary intracranial tumor, most common brain tumor in
childhood
Astrocytoma
a.k.a Pleocytic astrocytoma of the cerebellum
UMN or LMN Lesion
Tendon Reflexes: Normal to exaggerated
Upper Motor Neuron Lesion
UMN vs LMN Lesion
Withdrawal reflexes: Normal
Lower Motor Neuron Lesion
UMN or LMN Lesion
Tendon Reflexes: Normal to exaggerated
Upper Motor Neuron Lesion
UMN or LMN Lesion
Tendon Reflexes: Decreased to absent
Lower Motor Neuron Lesion
25% of brain tumors
Meningiomas
50-60% of brain tumors
Glial Tumors
UMN or LMN Lesion
Postural Reaction: Delayed to absent
Upper Motor Neuron Lesion