Neurological Disorders

Question 1

TB meningitis CSF

Answer 1

CSF: lymphocytic pleocytosis, decreased glucose,
increased protein

Question 2

Bacterial Meningitis would commonly present with:

TRIAD:

Answer 2

fever, headache, nuchal rigidity

Question 3

Guillain-Barré syndrome is managed with …

Answer 3

Spontaneous recovery may occur,
Plasma- pheresis., IVIG

Question 4

What is Guillain-Barré syndrome ?

Answer 4

> It is an acute inflammatory polyradiculoneuropathy
Seen in young-middle aged population
It is preceded by URTI or GI infection (C. jejuni),

Question 5

Epidural Hematoma would present with:

Answer 5

Lucid interval after brief consciousness ff by increasing obtundation, extreme headache, contalateral hemiparesis

Question 6

This is the most fatal form of extrapulmonary TB

Answer 6

TB Meningitis

Question 7

Management of Bacterial Meningitis?

Answer 7

dexamethasone + antibiotics

Question 8

This infection predominantly
involves the subarachnoid space (meninges)

Answer 8

ACUTE MENINGITIS

Question 9

TB Meningitis complications would present with:

Answer 9

hydrocephalus, cerebral
infarctions

Question 10

Cranial CT of TB Meningitis would present with?

Triad

Answer 10

1. Basal enhancement
2. Communicating hydrocephalus
3. Multiple vascular
   infarcts

TBM Cranial CT scan Triad

Question 11

Management of TB Meningitis would include:

Answer 11

2 HRZE + 10 HR + corticosteroids

Question 12

Most common form of suppurative CNS infection

Answer 12

Bacterial Meningitis

Question 13

SUBDURAL HEMATOMA would present with:

Answer 13

o Acute - from high speed trauma, coma
from impact
o Subacute - days of lethargy then
deterioration
o Chronic - minor trauma, gradual
deterioration

Question 14

ACUTE MENINGITIS CSF would present with

Answer 14

Protein: >50 viral, bacterial, fungal 400
Glucose<40% of serum-bacterial
TB: Lymphocytic CSF

Question 15

What is Myasthenia Gravis

Answer 15

> Autoantibodies vs Acetylcholine receptor
Associated with thymic hyperplasia and Thymoma
Seen more often in F>M

Question 16

PARKINSON’S DISEASE

Answer 16

loss of nerve cells in
pigmented substancia nigra, locus ceruleus in
MB, globus pallidus, putamen

Question 17

Guillain-Barré syndrome is diagnosed with

Answer 17

high CSF protein levels

Question 18

This is seen in middle age group people and known to present with rapid progression of weakness.
This is also knwon to be the most common motor system disease with a combination of
UMN and LMN presentation.

Answer 18

AMYOTROPHIC LATERAL SCLEROSIS

Question 19

This is the focal infection with capsule

Answer 19

Abcess

Question 20

Etiology of Bacterial Meningitis may be from:

Answer 20

Hematogenous, parameningeal infection
(sinusitis, mastoiditis, otitis media, brain
abscess), trauma, surgery

Question 22

Most common pathogens of Bacterial Meningitis

Answer 22

> S. pneumoniae
N. meningitides
H. Flu

Others: L. monocytogenes (Atypical), Staph, Gram(-)bacilli

Question 23

Multiple Sclerosis presents with

Answer 23

Optic neuritis,vertigo,paresthesias, sensory loss, pain, incoordination, bladder dysfxn, nystagmus, internuclear ophthalmoplegia bilateral

Question 24

Guillain-Barré syndrome presents with …

Answer 24

Progressive ascending weakness,
areflexia

Question 25

Treatment of ALS

Answer 25

Riluzole

Question 26

Alzheimer's Disease

Answer 26

Neuritic plaques with Amyloid neurofibrillary tangles

Question 27

This is the focal infection without capsule

Answer 27

Cerebritis

Question 28

Bacterial Meningitis present in immunocompromised patients would have the following pathogens:

Answer 28

S. pneumoniae, L. monocytogenes, H. flu

Question 29

Management of Myasthenia Gravis

Answer 29

Cholinestrase Inhibitors Steroids, Plasmapheresis, Thymectomy, IVIG

Question 30

What is Multiple Sclerosis?

Answer 30

> A demylenating disease with multiple areas of neurological deficits > Peaks on the 20th-24th year of life > Mostly seen in women > Unknown etiology (probably auto immune)

Question 31

Myasthenia Gravis Presentation

Answer 31

Weak with activity, fatigue, ocular symptoms

Question 32

ACUTE MENINGITIS presents with

Answer 32

Headache, fever, stiff neck, positive Kernigs and Brudzinskis, if viral, minimal neuro deficit

Question 33

Multiple Sclerosis is managed with..

Answer 33

Acute- IV or oral steroids

Question 34

Bacterial Meningitis involved with trauma or neurosurgery would have the following pathogens:

Answer 34

Staph, gram (-) bacilli, S. pneumoniae

Question 35

Viral Meningitis Diagnostics would include the following results: ## Footnote upon lumbar tap

Answer 35

DX: Aseptic CSF, lymphocytic, normal Glucose

Question 36

Viral Meningitis would involve:

Answer 36

infection involves brain tissue; focal signs, acute febrile illness, seizures, coma, headache fever nuchal rigidity