Tumors

Question 1

Histologies findings related to serous ovarian tumors

Answer 1

Psammoma bodies

Question 2

Histologies findings related to clear cell ovarian tumors

Answer 2

Hobnail cells

Question 3

Serum tumor marker of dysgerminoma?

Answer 3

LDH and alkaline phosphatase.Very good prognosis with oophorectomy and radio

Question 4

Hallmark of yolk sac tumor?

Answer 4

Schiller duval body. IHC positive for AFP

Question 5

How do we monitor tumor course of yolk Salk tumor?

Answer 5

AFP

Question 6

Treatment of yolk sac tumor?

Answer 6

Fatal without chemo as most have subclinical metastases at presentation even stage

Question 7

Serum markers of embryonal carcinoma?

Answer 7

Often present with precocious puberty, also vaginal bleeding, amenorrhea and hirsutism

• Serum hCG always high (positive pregnancy test), AFP sometimes high (if mixed)

Question 8

Histological findings of choriocarcinoma?

Answer 8

Malignant cyto and syncitiotrophoabst, no chrionic villi

Question 9

What IHC marker is positive in most sec cord tumors?

Answer 9

Alpha inhibin

Question 10

Name all the surface epithelium tumors with their main characteristics

Answer 10

-

Question 11

Name all the germ cell tumors with their main characteristics

Answer 11

-

Question 12

What could embroynal carcinoma present with?

Answer 12

Precocious puberty

Question 13

What could juvenile germ cell tumor present with?

Answer 13

Precocious puberty

Question 14

What does adult onset granulosa cell tumor present with

Answer 14

Metrrorhagia

Question 15

First line treatment of ovarian germ cell tumors

Answer 15

Conservative surgery in the form of salpingoopherectomy is the first line of treatment.

Question 16

Characteristic microscopic appearance in yolk sac tumors?

Answer 16

Schiller duval bodies.