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Neuro-oncologia > Tumores > Flashcards

Tumores Flashcards

1
Q

Loc + frecuente GB

A

Lobo temporal

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2
Q

Loc + F oligodendroglioma

A

Lob Frontal

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3
Q

Mutación fundamental para clasificación gliomas y asociada a mejor pronóstico

A

IDH

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4
Q

QT en gliomas bajo grado

A

Procarbazina, Vincristina, Lomustina

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5
Q

Primario +F de metástasis cerebral

A

Pulmón

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6
Q

mutación que define oligodendroglioma

A

1p/19q codeleted

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7
Q

RAM temozolamida

A

leucopenia, trombopenia

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8
Q

patrón espectroscopía glioblastoma multiforme

A

elevación de COLINA, LACTATO, LÍPIDOS

descenso NAA, MIOINOSITOL

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9
Q

REPERCUSIÓN MGMT EN RESPUESTA A TRATAMIENTO EN GLIOBLASTOMA

A

LA METILACIÓN (SILENCIAMIENTO) MGMT MEJORA LA RESPUESTA A AGENTES ALQUILANTES

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10
Q

QUÉ TUMOR ES MUY SENSIBLE A RADIOTERAPIA

A

MEDULOBLASTOMA

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11
Q

QUÉ TUMOR PRODUCE ERITROPOYETINA

A

HEMANGIOBLASTOMA

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12
Q

en qué tumor células tienen aspecto de huevo frito

A

en oligodendroglioma

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13
Q

oligodendroglioma puede ser de grado IV si hay necrosis

A

no

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14
Q

fibras de rosenthal, en que tumor se ven

A

astrocitoma pilocítico

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15
Q

tumor primario más frecuente

A

astrocitoma pilocítico

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16
Q

tumor primario SNC que puede tener MTX extracraneales

A

MEDULOBLASTOMA

17
Q

localización + F meningioma

A

a ambos lados seno longitudinal superior

18
Q

variedad de meningioma que se localiza en seno esfenoidal

A

meningioma difuso o en placa

19
Q

alteraciones genéticas en meningiomas malignos

A

pérdida de cromosoma 22 y mutaciones en NF2

20
Q

cuál es el ppal factor pronóstico en meningioma

A

completa resección, se establece con escala Simpson

21
Q

qué dato molecular en meningioma predice riesgo de recidiva

A

ki67>10%

22
Q

loc. más F de cordoma

A

clivus esfeno-occipital

sacro

23
Q

origen celular del cordoma

A

estirpe mesodérmica, restos de notocorda

Neuro-oncologia (3 decks)

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