Tumor Suppressors Flashcards by David Shin | Brainscape

Q

Rb

A

Retinoblastoma, osteosarcoma

Blocks G1 => S phase of cell cycle

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

p53

A

Most human cancers, Li-Fraumeni syndrome

Blocks G1 => S phase of cell cycle

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

BRCA1

A

Breast/Ovarian cancer

DNA repair protein

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

BRCA2

A

Breast cancer

DNA repair protein

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

p16

A

Melanoma

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

APC

A

Colorectal cancer (associated with FAP)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

WT1

A

Wilms’ tumor

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

NF1

A

Neurofibromatosis type 1

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

NF2

A

Neurofibromatosis type 2

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

DPC

A

Pancreatic cancer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

DCC

A

Colon cancer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly