Oncogenes Flashcards

1
Q

abl

A

CML

Tyrosine kinase

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2
Q

c-myc

A

Burkitt’s lymphoma

Transcription factor

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3
Q

bcl-2

A

Follicular and undifferentiated lymphomas

Anti-apoptotic molecule

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4
Q

erb-B2

A

Breast, ovarian, and gastric carcinomas

Tyrosine kinase

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5
Q

ras

A

Colon carcinoma

GTPase

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6
Q

L-myc

A

Lung tumor

Transcription factor

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7
Q

N-myc

A

Neuroblastoma

Transcription factor

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8
Q

ret

A

Multiple endocrine neoplasia (MEN) types IIA and IIB

Tyrosine kinase

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9
Q

c-kit

A

Gastrointestinal stromal tumor (GIST)

Cytokine receptor

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