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Step 1 Flash Cards > Tumor suppressor genes and their associated cancers > Flashcards

Tumor suppressor genes and their associated cancers Flashcards

1
Q

The Rb gene is assc with which cancer?

A

Retinoblastoma (Rb)

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2
Q

p53

A

Most human cancers; Li-Fraumeni syndrome

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3
Q

BRCA1 and BRCA2

A

breast and ovarian cancer

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4
Q

p16

A

Melanoma

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5
Q

BRAF

A

Melanoma

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6
Q

APC

A

Colorectal cancer

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7
Q

WT1

A

Wilm’s Tumor

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8
Q

NF1

A

Neurofibromatosis type 1

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9
Q

NF2

A

Neurofibromatosis type 2

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10
Q

DPC4

A

Pancreatic cancer (DPC stands for Deleted in Pancreatic Cancer)

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11
Q

DCC

A

Colon cancer (DCC stands for Deleted in Colon Cancer)

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Step 1 Flash Cards (3 decks)

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