Oncogenes and their associated tumors Flashcards

1
Q

The abl oncogene is associated with which tumor?

A

CML

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2
Q

c-myc

A

Burkitt’s lymphoma

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3
Q

bcl-2

A

Follicular and undifferentiated lymphomas (inhibits apoptosis)

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4
Q

HER2/neu

A

breast, ovarian, gastric carcinomas

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5
Q

ras

A

colon carcinoma

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6
Q

L-myc

A

Lung tumor (L and L)

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7
Q

N-myc

A

Neuroblastoma (N and N)

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8
Q

ret

A

multiple endocrine neoplasia (MEN) types 2A and 2B

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9
Q

c-kit

A

Gastrointestinal stromal tumor (GIST)

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