Tumor Microenvironment Flashcards
1
Q
stroma
A
This consists of basement membrane, fibroblasts, immune cells, connective tissue, blood vessels, inflammatory cells, all of which are interposed between
malignant cells and normal host tissues. In all tumors, the tumor is the product of the host and is induced by tumor cell - host interactions.
2
Q
CYPA34
A
CYPA34 stands for Cytochrome P450 3A4. This is an important enzyme found in the body that is found in the liver and intestine. It oxidizes small foreign molecules (xenobiotics) such as toxins or drugs that can be expelled from the body.
3
Q
CXCR4
A
CXC Chemokine Receptor 4 also known as fusin or CD184 is a protein encoded by the CXCR4 gene.
