Tumor markers and associated tumor/dz Flashcards

1
Q

Alk Phos

A

metastasis to bone, liver, paget dz of bone, seminoma (placental ALP)

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2
Q

alpha-fetoprotein

A

hepatocellular carcinoma, hepatoblastoma, yolk sack tumor, testicular cancer, mixed germ cell tumor (co-secreted w/ beta-hCG)… also normally made by fetus

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3
Q

beta-hCG

A

Hydatidiform mole and choriocarcinoma (gestational trophoblastic dz), testicuar cancer

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4
Q

CA-15-3/CA-27-29

A

breast cancer

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5
Q

CA-19-9

A

pancreatic adenocarcinoma

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6
Q

CA-125

A

Medullary thyroid carcinoma

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7
Q

CEA (CarcinoEmbryonic Antigen)

A

Non-specific … but, colorectal, pancreatic, gastric, breast, & medullary thyroid carcinomas

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8
Q

PSA

A

Prostate adenocarcinoma (also elevated in BPH & prostatitis)

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9
Q

S-100

A

Neural crest origin (melanoma, neural tumor, schwannoma, langerhans cell histiocytosis)

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10
Q

TRAP (Tartrate-Resistant Acid Phosphate)

A

Hairy cell leukemia

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