Tumor markers and associated tumor/dz Flashcards
Alk Phos
metastasis to bone, liver, paget dz of bone, seminoma (placental ALP)
alpha-fetoprotein
hepatocellular carcinoma, hepatoblastoma, yolk sack tumor, testicular cancer, mixed germ cell tumor (co-secreted w/ beta-hCG)… also normally made by fetus
beta-hCG
Hydatidiform mole and choriocarcinoma (gestational trophoblastic dz), testicuar cancer
CA-15-3/CA-27-29
breast cancer
CA-19-9
pancreatic adenocarcinoma
CA-125
Medullary thyroid carcinoma
CEA (CarcinoEmbryonic Antigen)
Non-specific … but, colorectal, pancreatic, gastric, breast, & medullary thyroid carcinomas
PSA
Prostate adenocarcinoma (also elevated in BPH & prostatitis)
S-100
Neural crest origin (melanoma, neural tumor, schwannoma, langerhans cell histiocytosis)
TRAP (Tartrate-Resistant Acid Phosphate)
Hairy cell leukemia