Tumor Markers Flashcards

0
Q

what type of cancer does and elevated human Chorionic Gonadotropin (hCG) indicate

A

testicular

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1
Q

What does elevated alpha-fetoprotein (AFP) indicate

A

HCC, testicular CA

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2
Q

Elevated Lactate Dehydrogenase (LDH) may indicate these cancers (4)

A

testicular, melanoma, lymphoma, leukemia

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3
Q

elevated Carcinoembryonic Antigen (CEA - most widely used tumor marker) may indicate this cancer

A

colorectal cancer

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4
Q

elevated CA 19-9 may indicate this disease (2)

A

pancreatic cancer, hepatobiliary cancer

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5
Q

Presence of BRCA-1 or BRCA-2 is assoc with…

A

breast and ovarian cancer

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6
Q

What type of tumor does elevated CA-125 indicate

A

ovarian

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7
Q

What tumors increase 5-Hydroxyindoleacetic acid (5-HIAA) urine levels?

A

carcinoid (seratonin-secreting) tumors (from neuroectoderm)

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8
Q

What tumor burdens do chromogranin A correlate with

A

carcinoid

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9
Q

platelet malignancy affecting Ig production

A

multiple myeloma

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10
Q

serum protein electrophoresis (SPEP) is used to detect “M-spike” of this disease

A

multiple myeloma

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