Tumor Markers Flashcards
what type of cancer does and elevated human Chorionic Gonadotropin (hCG) indicate
testicular
What does elevated alpha-fetoprotein (AFP) indicate
HCC, testicular CA
Elevated Lactate Dehydrogenase (LDH) may indicate these cancers (4)
testicular, melanoma, lymphoma, leukemia
elevated Carcinoembryonic Antigen (CEA - most widely used tumor marker) may indicate this cancer
colorectal cancer
elevated CA 19-9 may indicate this disease (2)
pancreatic cancer, hepatobiliary cancer
Presence of BRCA-1 or BRCA-2 is assoc with…
breast and ovarian cancer
What type of tumor does elevated CA-125 indicate
ovarian
What tumors increase 5-Hydroxyindoleacetic acid (5-HIAA) urine levels?
carcinoid (seratonin-secreting) tumors (from neuroectoderm)
What tumor burdens do chromogranin A correlate with
carcinoid
platelet malignancy affecting Ig production
multiple myeloma
serum protein electrophoresis (SPEP) is used to detect “M-spike” of this disease
multiple myeloma