Tumor Markers Flashcards

1
Q

Tumor Markers

A

Should not be used for primary diagnosis of cancer but instead used with a definitive diagnosis via biopsy. They may also be used to monitor tumor recurrence and response to therapy.

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2
Q

Alkaline Phosphatase (ALP)

A

Metastasis to bone and liver

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3
Q

Alpha-fetoprotein

A

Normally made by a fetus. Hepatocellular Carcinoma, Hepatoblastoma, yolk sac tumor, testicular cancer, mixed germ cell tumor

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4
Q

B-hCG

A

Choriocarcinoma, Testicular Cancer

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5
Q

CA 19-9

A

Pancreatic Adenocarcinoma

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6
Q

CA-125

A

Ovarian Cancer

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7
Q

Calcitonin

A

Medullary Thyroid Carcinoma

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8
Q

CEA (CarcinoEmbryogeninc Antigen)

A

Very nonspecific but produced by ~70% of colorectal and pancreatic cancers; also produced by gastric, breast, and medullary thyroid carcinomas

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9
Q

PSA (Prostate Specific Antigen)

A

Used to follow prostate adenocarcinoma.

**Could be elevated in BPH and prostatitis

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