Tularemia Flashcards

1
Q

Most virulent sps of tularemia ? Region and mortality

A

North America
A and 5-5%

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2
Q

Talk about tyoe B

A

Mortality less than 5% and it causes tularemia in Europe and asia

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3
Q

List the forms of tularemia

A

Ulceroglandular
Glandular
Typhoidal
Pneumonic
Septic
Oculoglandular
Oropharyngeal

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4
Q

List the routes if transmissions

A

Skin - handling infected animals
GIT coining contaminated meat poorly
Resp tract. Aerosol inhalation

Skin- bite of blood sucking deer flies and wood ticks

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5
Q

What hemisphere is tuleremia highly prevalent

A

The northern

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6
Q

They form spores

A

They do not

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7
Q

Found in where

A

Soul water moist hay straw decaying animal carcasses

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8
Q

Considering the reservoirs
What size are the natural reservoirs

A

Small and medium sized
Rabbits
Rats
Muskrats
Squirrels
Lemmings
Mice

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9
Q

List some vectors

A

Ticks
Mosquitos
Biting flies

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10
Q

Which mosquito transmits tuleremia

A

Culex mosquitos

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11
Q

Francisella tularemia is a _____ staining … ______gram ______

A

Weakly staining
Negative
Coccibacilli

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12
Q

Size

A

0.2-0.7 nm

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13
Q

Considering the morphology of the organism is it motile or not

A

Not

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14
Q

what stain ?

A

Giemsa stain
Bipolar staining

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15
Q

Catalase positive or negative

A

Positive

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16
Q

Young cultures are ______ in appearance and older cultures show ________

A

Uniform … pleomorphism

17
Q

Carbs are disssimilated______ with the ________

A

Slowly with the production of acid but no gas

18
Q

Has a capsule.. describe

A

It has a thick capsule and it is responsible for the virulence

19
Q

Lipid conc in the capsule and cell wall values

A

50:70

20
Q

Regarding culture characteristics
1. Optimal growth and growth range
2. _____ growing with requirement _____

A

37
24-39

Slow growing
Iron and cysteine

21
Q

What about hemolysis

A

No true hemolysis just greenish discoloration

22
Q

Treatment of tularemia

A

Tetracyclines and chloramphenicol

23
Q

WHich detection method is more accurate and sensitive

A

TRF is more accurate than ELISA

24
Q

List other detection systems

A

Mass spectrometry
TRF
ELISA
PCR

25
Q

Vaccines can’t be used for treatment after exposure why

A

TKes too long to have effect