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Micro > Brucellosis Dem Dem > Flashcards

Brucellosis Dem Dem Flashcards

1
Q

What animals does brucellosis affect

A

Farm animals( cattle sheep swine goats

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2
Q

How do they generally acquire the disease

A

Through direct contact with infected animals , drinking unpasteurized milk and whatnot

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3
Q

What are the symptoms

A

Flu like
Fever weakness malaise and weight loss

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4
Q

Which groups of people are at greater risk

A

People who work in labs containing such bacteria , also abbatoirs and their employees

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5
Q

About the Brucella spp
Gram n or p

A

Negative

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6
Q

What is the shape

A

Coccobacillus

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7
Q

Respiration

A

Facultative intracellular

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8
Q

This spps presents with environment persistence?

A

T ( harsh weather drying, freezing , dust soil)

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9
Q

Clinical presentation
What is perculiar about their existence

A

Flu like symptoms .. muscle pain joints pain
Fatigue
Note that some signs and symptoms may persist and others may never go away or reoccur

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10
Q

Incubation period

A

Variable
5 days to three months

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11
Q

It does not affect any organ or organ system

A

T or false

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12
Q

Isolation of organsism is by what specimen

A

Blood, bone marrow

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13
Q

Other diagnosis

A

Serum agglutination test
Immunofluorescence
PCR

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14
Q

Treatment

A

Doxycycline
Streptomycin
Rifampicin

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15
Q

What do you use in pregnancy

A

Rifadin + co trimoxazole

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16
Q

Talk about causes involving the CNS

A

Treat 6-9 months
Same for endocarditis

17
Q

Prognosis
If treated
Case fatality rate if the untreated
% of relapsed cases and why

A

Rarely Fatal if treated
2%
5% - failure to complete treatment and superimposed infections that require surgical intervention

Meaning it has a good prognosis

18
Q

What is the major cause of death of this disease

A

Endocarditis and meningitis

19
Q

Is there is a vaccine for humans and animals

A

No human vaccine but there is a vaccine for young goats and sheep and calves

20
Q

What is the causative organism for meloidosis

A

Burkholderria pseudomallei

21
Q

Gram stain and is prevalent in which country has

A

Negative … South East Asia

22
Q

What is it characterized by

A

Sepsis and abscess formation

23
Q

Mortality rate and who does it affect

A

40%
People who are in regular contact with soil and water

24
Q

It is a seasonal disease prevalent in which season

A

Rainy season

25
Q

It is oxidase ________

A

Positive

26
Q

How do you identify the organism

A

Oxidase positive
Inability to assimilate Arabinose
Colony morphology ( metallic sheen)

27
Q

Talk about the antimicrobial drug susceptibility

A

Resistant to gentamicin and colistin

Susceptible to amoxicillin clavulanic acid

28
Q

The organism is specific for which test

A

Latex agglutination
IHA

29
Q

What are the advantages of latex agglutination

A

Rapid simple to learn and inexpensive

30
Q

What is the organism for pertussis

A

Bordetella pertussis

Micro (3 decks)

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