Tuberculosis

Question 1

What is TB

Answer 1

A chronic bacterial infection that is primarily in the lung but can affect any part of the body

Question 2

Initial presentation of TB

Answer 2

Will initially present as pnuemonia, but some of the caili will survive and by walled off by the immune system (Ghon Lesions)

Question 3

TB Diagnostic Tests

Answer 3

Mantoux, actid fast satin, sputum culture, QuantiFERON (gold standard)

Question 4

Mantoux Tuberculin Test

Answer 4

Wheal <5 mm = Negative
Wheal 5-9 mm= Consider suspicious in non-high-risk categories
*With high risk categories (exposure, ghon lesions, HIV, under age 5) it is considered a positive result
Wheal 10 mm of greater=Positive

Question 5

QuentiFERON

Answer 5

QuentiFERON is a blood test that will give results after 24 hours, but unable to distinguish between active vs latent TB infectiosn

Question 6

Primary Bacteria that causes TB

Answer 6

mycobacterium tuberculosis

Question 7

TB chest x-ray

Answer 7

Increased opacity, ghon nodule, cavities, effusion, calcificiation and fibrosis

Question 8

TB PFT

Answer 8

Restrictive presentation

Question 9

TB Hemodyanmics

Answer 9

Pulmonary HTN

Right sided heart failure

Question 10

TB Pharmacology

Answer 10

Isoniazid is the most effect first line anti TB agent

Rifampin bactericidal and communly used with isoniazid

Question 11

Ghon Lesions

Answer 11

Ghon Lesion is the only abnormal thing you would see in latent TB and may not always be there