Tuberculosis Flashcards

1
Q

Initial Phase:

A

Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
RIPPPPPPE
TWO MONTHS

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2
Q

Continuation Phase:

A

Rifampicin
Isoniazid

FOUR MONTHS

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3
Q

Vitamin B6 also

A

peripheral nephropathy

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4
Q

Latent Tb

A

3 months of of Rifampicin and isoniazid or 6 months of isoniazid

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5
Q

TB medication

A
  • Patients with latent TB aged 35-65 years should be cleared of hepatotoxicity
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6
Q

Rifampicin:

A
  • Discolours soft contact lenses and bodily fluids orangey -red colour
    • Enzyme inducer - CYP450 interaction
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7
Q

Isoniazid

A
  • Peripheral neuropathy - give prophylactic pyridoxine hydrochloride (vitamin B6)
    • Enzyme inhibitor - CYP450 INTERACTION
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8
Q

Pyrazinamide

A

hepatoxicity

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9
Q

Ethambutol

A

visual impairment +ocular toxicity

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