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protozoology > trypanosoma > Flashcards

trypanosoma Flashcards

0
Q

trypansomes are intercellular except _____________ which is intracellular

A

T. cruzi

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1
Q

trypanosome occur in _________ & _________

A

blood

tissue fluids

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2
Q

T. cruzi is found where?

A

cells of RE system

cardiace muscles

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3
Q

disease produced by trypanosomes

A

trypanosomiosis

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4
Q

transmission occurs by blood sucking parasites except __________

A

T. equiperdum in equines (by coitus)

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5
Q

transmission can be _______ or ________

A

cyclical

non-cyclical

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6
Q

cyclical transmission can occur by twi ways

A

anterior station development(foregut)

posterior station development(hindgut)

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7
Q

anterior station development occurs in __________ of insect and infection of __________is tranmitted fly bite

A

proboscis and salivary glands

trypomastigote(infective stahe)

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8
Q

parasites transmitted by posterior station are non pathogenic TRUE or FALSE

A

TRUE

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9
Q

give example of ANTERIOR STATION TRANSFER

A

T. congolense
T. vivax
t. brucei

they are transmitted by TSE TSE fly

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10
Q

give an example of POSTERIOR STATION DEVELOPMENT

A

T. theileri(tabanid flies)
T. melophagium(melophagus ovinus/sheep ked)
T. cruzi(reduviid bug)

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11
Q

mechanical transmission is also known as

A

non-cyclical transmission

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12
Q

example of mechanical transmission

A

T. evansi(biting flies)

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13
Q

in well developed trypanosomal infection in vertebrates, the surface antigens change every few _______

A

days

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14
Q

full form of VAT

A

variant antigen type

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15
Q

heavy antigen coating is found on surface of ___________ only

A

trypomastigote

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16
Q

only __________ stage of trypanosome is responsible for antigenic changes

A

trypomastigote

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17
Q

the surface coat is made up of __________ identical glycoprotein molecules

A

10 lakh

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18
Q

these identical glycoprotein molecules are known as _______

A

VSG

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19
Q

enumerate VSG

A

variant suface glycoprotein

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20
Q

under what conditions, glycoprotein coat of trypanosome is lost

A
  • after entering VECTOR(either cyclical or mechanical)

- during IN VITRO culture

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21
Q

the immunological response of host to salivarian & stercorarian trypanosome is different TRUE or FALSE

A

TRUe

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22
Q

Salivarian trypanosomes produce _______ parasitemia in host

A

ascending

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23
Q

the immune response againt Salivarian tryoanosomes is mediated by ______ & ______ antibodies

A

IgG

IgM

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24
Q

first trypanosome shown to be pathogenic to mammals

A

T. evansi

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25
Q

first parasitic protozoa observed in microscope

A

Eimeria stiedae

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26
Q

T. evansi was identified by _______

A

griffith evans

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27
Q

diseases caused by T. evansi

A

surra
tibersia
gufar

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28
Q

vector of T. evansi

A

tabanid flies & other blood sucking arthropods

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29
Q

forms lacking kinetoplast arise after _________

A

drug treatment

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30
Q

T. evans does not survive in the proboscis of flies for more than _____ minutes

A

10-15

31
Q

the most common clinico-pathological findings in T. evansi infection is ______________

A

progressive anaemia

32
Q

causes for progressive anaemia

A

haemolysins
immunoglobulin antigen complex on RBC
depression of erythropoiesis

33
Q

in T. evansi infection ____________ is considered to be cause of death

A

hypoglycemia

34
Q

hypoglycemia occurs due to direct utilisation of glucose by T. evansi
TRUE or FALSE

A

FALSe

35
Q

why hypoglycemia occurs in T . evansi infection?

A

metabolism of carbohydrate is disturbed due to malfunction of adrenals,pancreas and thyroid

36
Q

in T. evansi infection in horse, the main symptoms are

A 
intermittent fever(rising to 44 C)
anaemia
37
Q

in T. evansi infection in horses, petechial haemorrhages area seen on

A

mucuous membreane of eye

vulva of mare

38
Q

in T. evansi infection of horses,
urine becomes _________ in color
_________ tinged mucous discharge from nostrils
plasma takes _______ tinge

A

dark yellow
yellow
red

39
Q

in T. evansi infection of horse, __________ accompanies febrile paroxysm(fever burst)

A

urticarial eruptions(on neck,flank)

40
Q

__________ species is considered to be main reservoirs of T. evansi infection in horse

A

Cattle & buffalo

41
Q

buffalo have higher incidence rate of T. evansi infection than Cattle
TRUE or FALSE

A

TRUE

42
Q

in acute disease of T. evansi, death occurs in ______ hours in cattle & buffalo

A

6-12

43
Q

in T. evansi infection of Cattle & buffalo, temperature rise is seen upto ______

A

40.6 C

44 C is horse

44
Q

in PERACUTE cases of T. evansi infection of Cattle & buffalo, nervous signs develop in ______hours

A

2-3

45
Q

in T. evansi infection of Cattle & buffalo, BILATERAL LACRIMATION is seen in

  1. peracute
  2. acute
  3. subacute
  4. chronic
A

subacute & chronic

46
Q

surra means

A

rotten

47
Q

T. evansi was first seen in ________

A

camel

48
Q

T. evansi infection in camel is known as _______

A

tibersia

49
Q

tibersia means

A

3 year duration

50
Q

main character of T. evansi infection in camel

A

hump disappears

51
Q

main character of SURRA in dogs & cats

A

voice of dog changes, similar to RABIES

52
Q

why does voice changes in SURRA in dog & cat

A

oedema of larynx

53
Q

T. evansi is not pathogenic to _______ species

A

PIG

54
Q

blood smears taken at peak of fever are ________(+ve/-ve)for parasite

A

positive

55
Q

arrange the parasite in decresing order of size
evansi
theileri
equiperdum

A

theileri>evansi>equiperdum

56
Q

____________ are most suitable hosts for detcting subpatent T. evansi infection

A

albino mice & rat(DOG for T. equiperdum)

57
Q

in white mice, ______ ml of blood is inoculated intra_________

A

0.5

intraperitoneally

58
Q

drugs for treatment of trypanosomiosis

A

quinpyramine
suramin
diamidine
phenanthridine

59
Q

difference of T. equipardum from t. evansi

A

smaller size

lesser motility

60
Q

disease caused by T. equiperdum

A

dourine
equine syphilis
breeding paralysis

61
Q

dourine means

A

dirty

62
Q

T. equiperdum is transmitted by

A

coitus

63
Q

clinical dourine has ___ phases

A

3

64
Q

name the 3 phases of dourine

A
  1. phase of OEDEMA
  2. URTICARIAL phase
  3. phase of PARALYSIS
65
Q

aobrtion occur in which phase of dourine

A

1st i.e. phase of OEDEMA

66
Q

pathogonomic lesion of dourine are

A

dollar spot

67
Q

dollar spots are seen in which phase of dourine

A

2nd i.e. 7

URTICARIAL phase

68
Q

in phase of paralysis in dourine, the effected parts are

A

hind legs
lips
nostril
ears

69
Q

________ is most suitable host for detecting T . equipardum infection

A

dog

70
Q

largest species or genus Trypanosoma

A

T. theileri

71
Q

in T. theileri infection , which forms of parasite occur in blood?

A

trypomastigote

epimastigote

72
Q

T. theileri is trasmitted __________ in __________ station of ________ flies

A

cyclically
posterior
tabanid

73
Q

T. theileri is associated with _________ disease

A

turning sickness

74
Q

diagnosis of T. theileri

A

by cultivation of trypanosomes on NNN

75
Q

NNN stands for

A

Novy
McNeal
Nicolle

protozoology (15 decks)

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