TRYPANOSOMA Flashcards

1
Q

first reported human infection with the zoonotic parasite

A

trypanosoma evansi

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2
Q

typanosomosis in philippines

A
  • introduced in to luzon in 1900 from chian
  • widespread in the country
    -large serious outbreaks in mindanao in previous years
  • present: sporadic outbreak
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3
Q

-2-3 leishmania amastigote maybe the smallest eukaryotic cells
- flagellum is vey short, projecting only slightly beyond the flagella pocket.

A

Trypanosoma
Amastigote (leishmanial)

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3
Q

kinetoplast and kinetosome are still located between the nucleus and the anterior edn, but a short undulating membrane lies along the proximal part of the flagellun.

A

Trypanosoma
Epismastigote (Crithidial)

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3
Q

kinetroplast and kinetosome are near to the posterior end of the body
-flagellum runs along the surface, usually continuing as a free whip anterior to the body

A

Forms of Trypanosoma
Trypomastigote (trypanosome)

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3
Q

-elongated body with flagella extending forward as a functional organelle
-kinetosome and kinetoplast are located in front of nucleus, near the anterior end of the body.

A

Trypanosoma
promastigote (leptomonad)

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4
Q

Section of trypanosoma
trypanosoma are divided into two broad group:

A
  1. Hemoflagellates
  2. Mucoflagellates
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4
Q

blood and tissue parasites

A
  1. Hemoflagellates
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5
Q

Trypanosoma are divided into two groups:

A
  1. Salivaria
  2. Stercorarcia
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6
Q

develops at the anterior portion of the digestive tract (anterior station)

A

Salivaria

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6
Q

live in the mouth and the cecum/colon

A

2.Mucoflagellates

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7
Q

salivaria eg;

A

T.brucie spp., T.evansi, T. congolense, T. vivax

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8
Q

anterior station development; multiplication and transformation in the gut and proboscis; transmission is by feeding

A

SALIVARIA

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9
Q

develop at the vector’s hindgut( posterior station)

A

Stercocaria

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10
Q

Stercorarian eg;

A

T.cruzi, T. lewisi, T.theileiri, T. melophagium, T. canorini

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11
Q

Cyclical – arthropod intermediate host (biological) Types:

A

a. SALIVARIA
b. STERCORARIA

11
Q

posterior station development; multiplication in the gut; infective forms migrate to the rectum and passed out in the feces

A

STERCORARIA

11
Q

Do not require development in an intermediate host

A

Trypanosoma equiperdum and T. equinum

12
Q

mechanical transmission by Tabanids and Stomoxys; no cross transmission because trypanosomes die quickly

A

Noncyclical

13
Q

Modes of Transmission of Trypanosomes

A

Cyclical
Noncyclical
Coitus
Transplacental
Ingestion of fresh carcasses or organs of animals which died of the infection intrauterine

14
Q

Pathogenesis of trypanosomes

A

-Lymphoid enlargement- exhaustion of cellular elements.
-Hemolysis- failure of phagocytic system
-Cell degeneration and inflammatory infiltrate- tissue degeneration particularly the CNS and the heart muscles

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