TRUELEARN 19 NOV 2018 Flashcards

1
Q

what is the initial landmark during a laparoscopic Nissen?

A

gastrohepatic ligament

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2
Q

the ligamentum teres is the remnant of the _____________________

A

fetal umbilical vein

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3
Q

prior to dividing the gastrohepatic ligament during a Nissen, care must be taken to avoid what structure?

A

replaced left hepatic artery (from left gastric)

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4
Q

when does the damage from chronic radiation therapy occur?

A

6-12 months

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5
Q

what type of damage does chronic radiation therapy do?

A
  • direct damage to DNA

- oxygen free radicals

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6
Q

what characterizes the damage to blood vessels from chronic radiation therapy?

A

obliterative arteritis (progressive fibrosis of microvasculature - thickening of endothelium)

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7
Q

hypomagnesemia impairs release of what hormone?

A

PTH (and end organ response to PTH)

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8
Q

what is the most important parameter in determining if a patient can undergo lung resection? what is the threshold value for tolerance?

A
  • FEV1

- if greater than 0.8 L, will tolerate

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9
Q

if a patient’s FEV is too low to tolerate a lung resection, what test should you order?

A

VP scan

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10
Q

what stimulates the contraction of the gallbladder?

A

vagus nerve

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11
Q

what inhibits the motor activity of gallbladder contraction?

A

splanchnic sympathetic stimulation

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12
Q

what is the longest and most variable phase of the cell cycle?

A

G1

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13
Q

the majority of bile salts are absorbed via _____________ in the ____________

A
  • active transport

- terminal ileum

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14
Q

chemotherapy can be given during what trimesters?

A

2nd and 3rd (2% risk of fetal malformation)

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15
Q

what is the dohlman procedure?

A

endoscopic surgery for zenker diverticulum - divides cricopharyngeus while obliterating the sac (esophagus and diverticulum form a common channel)

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16
Q

what are the treatment options for zenker diverticula?

A
  • cricopharyngeal myotomy independent of size

- diverticulectomy for 2 cm or greater

17
Q

how is fibrolamellar HCC differentiated from FNH?

A

elevated neurotensin levels

18
Q

how is fibrolamellar HCC differentiated from HCC?

A

cluster of large polygonal cells interspersed with sheets of collagen

19
Q

the risk of death within a year is more than doubled if a hip fracture is not fixed within __ days in the elderly

A

2

20
Q

why is urine alkalinized in ABO incompatibility reactions?

A

to prevent precipitation of Hb

21
Q

nonhemolytic transfusion reactions are due to:

A

WBC in donor blood

22
Q

what is the diagnostic study of choice for budd-chiari?

A

doppler US

23
Q

what are the milan criteria?

A

to identify patients with HCC who would be good candidates for liver transplant:

  • single lesion less than 5 cm
  • up to three lesions, each less than 3 cm
  • no extrahepatic metastatic disease or major vessel involvement
24
Q

what is the serum marker for autoimmune pancreatitis? how is the sensitivity / specificity?

A
  • IgG4

- specific, but not sensitive

25
Q

what is the most appropriate imaging modality to detect a colovesicular fistula?

A

CT (for air in the bladder)

26
Q

resuscitation with NS is associated with what acid base abnormality?

A

non-anion gap hyperchloremic metabolic acidosis (excess chloride to sodium with a decrease in bicarbonate)

27
Q

lynch I syndrome is associated with what type(s) of cancer(s)?

A

colon

28
Q

lynch II syndrome is associated with what type(s) of cancer(s)?

A
  • endometrial
  • ovarian
  • gastric
29
Q

what are the amsterdam criteria used for? what are they?

A
  • used for screening hereditary nonpolyposis colorectal cancer
  • three or more first degree relatives with colon cancer
  • across two generations
  • one member must be diagnosed prior to the age of 50
30
Q

what are the components of the gail model?

A
  • current age
  • age at menarche
  • number of previous breast biopsies
  • age at first live birth
  • number of first degree relatives affected with breast cancer
  • race
31
Q

what are the margins for low risk basal cell carcinoma excision?

A

3-5 mm