trouble knowing

Question 1

a value that reflects affinity and is defined by the concentration of drug needed to ocuppy 50% of the receptors

Answer 1

Kd

Question 2

what does a low Kd indicate. what about when [a]=Kd?

Answer 2

low kd = drug binds to receptor well

[a]=Kd = 50% of the receptors are occupied by drug

Question 3

phase that tests for tolerable dosing range, bioavailability and excretion

Answer 3

phase 1

Question 4

testing for efficacy, and monitoring for safety

Answer 4

phase 2

Question 5

involves blinding, randomization , and comparing against a placebo or current accepted treatment

Answer 5

phase 3

Question 6

survellence in the market, used for detecting rare events

Answer 6

phase 4