Trophectoderm, primitive endoderm and epiblast Flashcards
1
Q
Where are cells with TE fate established?
A
Outside of morula in contact with extra embryonic fluid.
Draw diagram
2
Q
Where are cells with PrE fate established?
A
From ICM facing blastocoel
3
Q
Where are cells with EPI fate established?
A
From internal ICM
4
Q
What genes are expressed by cells with TE fate?
A
Cdx2, eomesodermin
5
Q
What genes are expressed by all ICM cells?
A
Oct4 (down regulate Eomes and Cdx2)
6
Q
What genes are expressed by cells with PrE fate?
A
GATA6, GNCF and Sox17
7
Q
What genes are expressed by cells with EPI fate?
A
nanog, Sox2, Stat3
8
Q
What do TE cells become?
A
Trophoblast stem cells, giant trophoblast cells, placenta
9
Q
What do PrE cells become?
A
Amnion (inner embryonic membrane)
10
Q
What do EPI cells become?
A
Embryo proper
