TREATMENTS Flashcards
psoriasis
emollients
- vit d analouges eg calcitriol
- coal tar
- dithranol
phototherapy
- UVB and PUVA
systemic treatments
- methotrexate
scalp psoriasis
- greasy ointment
- tar shampoo
- steroids in alcohol base or shampoo
- vit d analogues
axilla psoriasis
calcineural inhibitors
chronic plaque psoriasis
vit d analogues
moderate - potent topical steroids can be used
flexural psoriasis
mild steroid / topical cream
tacrolimus
guttate psoriasis
topical therapies and UBV
palmoplantar psoriasis
very potent topical steroids, tar paste or local hand / foot UBV
atopic eczema
for everyone - emmolients
for itch - antihistamines
for flare - topical steroids
calcineurin inhibitors (tacrolimus) = steroid sparing agent
phototherapy (UBV)
strengths eczema (steroids)
mild - hydrocortisone
moderate - betnovate, tacrolimus
severe - dermovate, UV light therapy, systemic immunosuppression
eczema herpeticum
IV aciclovir
seborrhoeic dermatitis
infantile cradle cap - emollients +- topical steroids
adults - emollients + topical steroid + topical antifungal (ketoconazole)
if non-responsive - oral antifungals
venous eczema
compression
PCT
- treat underlying cause (alcohol, viral hep)
2. low dose of antimalarials (chloroquine) –> works by removing excess porphyrins from liver
erythropoietic protoporphyria
- suncream containing zinc
- prophylactic TL-01 phototherapy using UBV lamp
- antioxidants
- 6 monthly LFTs
acute intermittent porphyria
- high carbohydrate if drug caused
acute attack = hematin and heme arginate
polymorphic light eruption
- topical steroids
- desensitising using UVB prior to sunlight use
dermatophyte infections
small areas
- clotrimazole cream
- topical nail pain - amorolfine
extensive
- terbinafine
- itraconazole
candida skin infections
clotrimazole cream
oral fluconazole
pityriasis vesicolour
- kerconazole
- green under woodlamp
scabies
malathion lotion or permethrin
lice
malathion lotion
acne vulgaris
topical
- benzyl peroxide
- topical vit A derivatives
- topical antibiotics
systemic
- antibiotics eg doxycycline for 6 months
- isotretinoin
mild acne vulgaris
topical therapy only (retinoid+ BPO / antibiotic eg erythromycin or clindamycin)
moderate acne vulgaris
topical therapy + oral antibiotic (erythromycin/ clindamycin) + contraceptive pill
severe acne vulgaris
topical therpaies
isotretinoin
rosacea
- topical therapy - metronidazole / ivremectin (to remove mite)
- oral therapy - tetracycline
- isotretinoin
potyriasis rosea
emollients and antihistamine
tuberose scleorosis
mTOR inhibitors
bullous pemphigoid
- systemic steroids
- topical treatments - emollients, topical steroids, topical antiseptics
pemphigus vulgaris
- tetracycline
local disease
- topical steroids + topical anaesthetics
systemic disease
- high dose steroids + immunosuppressive +- rituximab
chickenpox
dont take ibroprufen
shingles
no treatment
- acyclovir to speed up
herpes simlex virus
- analouge of guanosine
- oral aciclovir
erythema multiforme
if recurrent, aciclovir
dermatitis herpetiformis
- gluten free diet
- dapsone (rapid relief from itching and blistering
warts
- topical salicylic acid + mechanical pairing
syphilis
penicillin
lyme disease
- doxycyline or amoxicillin
necrotizing fascitis
- urgent surigcal debridement + antibiotics (group A = clindamycin + penicillin)
impetigo
localised - fusidic acid
MRSA - mupirocin
widespread / bullous - fluclox
SSSST
fluclox
cellulitis
- fluclox
- doxycyline
- IV fluclox / vancomycin if allergic
erysipelas (superficical cellulitis)
fluclox
folliculitis
topical antiseptic and loose clothing
boils / furnuncles
isolated boils - hot bathing alone
widespread - fluclox
PVL - rifampicin / clindamycin
larger boils - incision and drainage
Neurofibromatosis T1
MEK inhibitors
actinic keratosis
topical 5-flurouracil cream
imiquimoid cream
bowen’s disease
surgical - cryosurgery, cutterage, excision
medial - phododynamic therapy, topical imiquimoid, 5-FU
melanoma
- urgent excision biopsy / chemo
advanced
- dasatinib + imatininb = target c-kit
- vemurafenib = target BRAF
- trametinib = targets MEK
BCC
- excision + cryotherapy
superficial BCCs
- topical flurouracil or imiquimoid
morphoeic / on nose
- mohs surgery
SCC
- excision with minimal margin of 5mm
leg ulcer
- non-adherent dressing
- desloughing agent eg hydrogel
- compression stockings
- 4 layer compression bandaging
T1 allergy
- adreanline autoinjector (300 in adults, 150 in children)